MAPK8IP1
C-Jun-amino-terminal kinase-interacting protein 1 is a protein in humans that is encoded by MAPK8IP1 gene. The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Required for JNK activation in response to excitotoxic stress. Cytoplasmic MAPK8IP1 causes inhibition of JNK-regulated activity by retaining JNK in the cytoplasm and inhibiting JNK phosphorylation of c-Jun. May also participate in ApoER2-specific reelin signaling. Directly, or indirectly, regulates GLUT2 gene expression and beta-cell function. Appears to have a role in cell signaling in mature and developing nerve terminals. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (By similarity). Functions as an anti-apoptotic protein and whose level seems to influence the beta-cell death or survival response.
MAPK8IP1 Antibodies
MAPK8IP1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA013467GA01HU | MAPK8IP1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA003081 | MAPK8IP1 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA080012 | Phospho-MAPK8IP1 (T103) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA990282 | MAPK8IP1 Antibody | Human,Mouse,Rat | ELISA,WB |
MAPK8IP1 Proteins
MAPK8IP1 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP879514RA CSB-EP879514RA CSB-BP879514RA CSB-MP879514RA CSB-EP879514RA-B |
Recombinant Rat C-Jun-amino-terminal kinase-interacting protein 1 (Mapk8ip1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAPK8IP1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP892370HU CSB-EP892370HU CSB-BP892370HU CSB-MP892370HU CSB-EP892370HU-B |
Recombinant Human C-Jun-amino-terminal kinase-interacting protein 1 (MAPK8IP1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAPK8IP1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP894384MO CSB-EP894384MO CSB-BP894384MO CSB-MP894384MO CSB-EP894384MO-B |
Recombinant Mouse C-Jun-amino-terminal kinase-interacting protein 1 (Mapk8ip1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
