MAD2L2
Mitotic spindle assembly checkpoint protein MAD2B is a protein in humans that is encoded by MAD2L2 gene. Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1. Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation.
MAD2L2 Antibodies
MAD2L2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA013307GA01HU | MAD2L2 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA887064LA01HU | MAD2L2 Antibody | Human | ELISA |
| CSB-PA887064LD01HU | MAD2L2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA887064LC01HU | MAD2L2 Antibody, FITC conjugated | Human | |
| CSB-PA887064LB01HU | MAD2L2 Antibody, HRP conjugated | Human | ELISA |
| CSB-RA782379A0HU | MAD2L2 Recombinant Monoclonal Antibody | Human | ELISA, WB, IHC, IF |
MAD2L2 Proteins
MAD2L2 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP013307RA CSB-EP013307RA CSB-BP013307RA CSB-MP013307RA CSB-EP013307RA-B |
Recombinant Rat Mitotic spindle assembly checkpoint protein MAD2B (Mad2l2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAD2L2 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP633021XBF CSB-EP633021XBF CSB-BP633021XBF CSB-MP633021XBF CSB-EP633021XBF-B |
Recombinant Xenopus tropicalis Mitotic spindle assembly checkpoint protein MAD2B (mad2l2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAD2L2 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP639755BO CSB-EP639755BO CSB-BP639755BO CSB-MP639755BO CSB-EP639755BO-B |
Recombinant Bovine Mitotic spindle assembly checkpoint protein MAD2B (MAD2L2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAD2L2 Proteins for Gallus gallus (Chicken)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP680002CH CSB-EP680002CH CSB-BP680002CH CSB-MP680002CH CSB-EP680002CH-B |
Recombinant Chicken Mitotic spindle assembly checkpoint protein MAD2B (MAD2L2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAD2L2 Proteins for Dictyostelium discoideum (Slime mold)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP681717DKK CSB-EP681717DKK CSB-BP681717DKK CSB-MP681717DKK CSB-EP681717DKK-B |
Recombinant Dictyostelium discoideum Mitotic spindle assembly checkpoint protein MAD2B (mad2l2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAD2L2 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP704078DIL CSB-EP704078DIL CSB-BP704078DIL CSB-MP704078DIL CSB-EP704078DIL-B |
Recombinant Danio rerio Mitotic spindle assembly checkpoint protein MAD2B (mad2l2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAD2L2 Proteins for Xenopus laevis (African clawed frog)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP823126XBE CSB-EP823126XBE CSB-BP823126XBE CSB-MP823126XBE CSB-EP823126XBE-B |
Recombinant Xenopus laevis Mitotic spindle assembly checkpoint protein MAD2B (mad2l2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAD2L2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP875222MO CSB-EP875222MO CSB-BP875222MO CSB-MP875222MO CSB-EP875222MO-B |
Recombinant Mouse Mitotic spindle assembly checkpoint protein MAD2B (Mad2l2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MAD2L2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP887064HU CSB-EP887064HU CSB-BP887064HU CSB-MP887064HU CSB-EP887064HU-B |
Recombinant Human Mitotic spindle assembly checkpoint protein MAD2B (MAD2L2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
