KITLG
KITLG，即KIT配體，別名SCF、MGF、FPFH、DCUA等。它是一種由骨髓微環(huán)境中的基質(zhì)細(xì)胞產(chǎn)生的酸性糖蛋白，由兩個(gè)相同亞基非共價(jià)結(jié)合而成。KITLG的作用機(jī)制主要是通過與其受體c-Kit結(jié)合，激活下游的信號(hào)傳導(dǎo)途徑，如JAK/STAT、PI3K/AKT、ERK1/2和STAT3等，從而促進(jìn)細(xì)胞增殖、分化和遷移。KITLG在胚胎期的生殖細(xì)胞和神經(jīng)細(xì)胞發(fā)育、造血過程中發(fā)揮作用，成體中主要在造血過程中發(fā)揮作用。KITLG的異常表達(dá)與多種疾病相關(guān)，包括家族性進(jìn)行性高色素沉著癥、神經(jīng)性耳聾、某些類型的癌癥如鼻咽癌、膀胱癌和三陰性乳腺癌。KITLG在腫瘤微環(huán)境中的表達(dá)與腫瘤細(xì)胞的增殖、侵襲和轉(zhuǎn)移密切相關(guān)，是癌癥治療中的潛在藥物靶點(diǎn)。
熱銷產(chǎn)品
Recombinant Human Kit ligand (KITLG), partial (Active) (CSB-MP002061HU1)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
The ED50 as determined by the dose-dependent stimulation of the proliferation of MO7e cells is 1.813-3.203 ng/mL.
The purity of KITLG was greater than 95% as determined by SEC-HPLC
KITLG Antibodies
KITLG for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA012376ESR2HU | KITLG Antibody | Human | ELISA, WB |
| CSB-PA122514 | KITLG Antibody | Human | ELISA,WB |
KITLG Proteins
KITLG Proteins for Ovis aries (Sheep)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012376SH1 CSB-EP012376SH1 CSB-BP012376SH1 CSB-MP012376SH1 CSB-EP012376SH1-B |
Recombinant Sheep Kit ligand (KITLG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF012376SH | Recombinant Sheep Kit ligand (KITLG) | in vitro E.coli expression system |
KITLG Proteins for Felis catus (Cat) (Felis silvestris catus)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012376CA1 CSB-EP012376CA1 CSB-BP012376CA1 CSB-MP012376CA1 CSB-EP012376CA1-B |
Recombinant Cat Kit ligand (KITLG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF012376CA | Recombinant Cat Kit ligand (KITLG) | in vitro E.coli expression system |
KITLG Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012376RA1 CSB-EP012376RA1 CSB-BP012376RA1 CSB-MP012376RA1 CSB-EP012376RA1-B |
Recombinant Rat Kit ligand (Kitlg), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF012376RA | Recombinant Rat Kit ligand (Kitlg) | in vitro E.coli expression system |
KITLG Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-EP012376MO1 CSB-BP012376MO1 CSB-EP012376MO1-B |
Recombinant Mouse Kit ligand (Kitlg), partial | E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-AP003151MO | Recombinant Mouse Kit ligand protein (Kitlg), partial (Active) | E.Coli |
| CSB-CF012376MO | Recombinant Mouse Kit ligand (Kitlg) | in vitro E.coli expression system |
| CSB-AP004071MO | Recombinant Mouse Kit ligand (Kitlg), partial (Active) | E.coli |
KITLG Proteins for Mustela vison (American mink) (Neovison vison)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012376MVE CSB-EP012376MVE CSB-BP012376MVE CSB-MP012376MVE CSB-EP012376MVE-B |
Recombinant Mustela vison Kit ligand (KITLG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KITLG Proteins for Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012376DXJ CSB-EP012376DXJ CSB-BP012376DXJ CSB-MP012376DXJ CSB-EP012376DXJ-B |
Recombinant Coturnix coturnix japonica Kit ligand (KITLG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KITLG Proteins for Capra hircus (Goat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012376GO CSB-EP012376GO CSB-BP012376GO CSB-MP012376GO CSB-EP012376GO-B |
Recombinant Goat Kit ligand (KITLG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KITLG Proteins for Equus caballus (Horse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012376HO CSB-EP012376HO CSB-BP012376HO CSB-MP012376HO CSB-EP012376HO-B |
Recombinant Horse Kit ligand (KITLG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KITLG Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012376CH CSB-EP012376CH CSB-BP012376CH CSB-MP012376CH CSB-EP012376CH-B |
Recombinant Chicken Kit ligand (KITLG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KITLG Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012376BO CSB-BP012376BO CSB-MP012376BO CSB-EP012376BO-B |
Recombinant Bovine Kit ligand (KITLG), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KITLG Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP012376PI CSB-EP012376PI CSB-BP012376PI CSB-MP012376PI CSB-EP012376PI-B |
Recombinant Pig Kit ligand (KITLG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KITLG Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-EP012376HU | Recombinant Human Kit ligand (KITLG), partial | E.coli |
| CSB-AP002061HU | Recombinant Human Kit ligand protein (KITLG), partial (Active) | E.Coli |
| CSB-CF012376HU(A4) | Recombinant Human Kit ligand (KITLG) | in vitro E.coli expression system |
| CSB-AP003741HU | Recombinant Human Kit ligand (KITLG), partial (Active) | E.coli |
| CSB-AP003881HU | Recombinant Human Kit ligand (KITLG), partial (Active) | Mammalian cell |
| CSB-MP002061HU1h6 | Recombinant Human Kit ligand (KITLG), partial | Mammalian cell |
| CSB-MP002061HU1 | Recombinant Human Kit ligand (KITLG), partial (Active) | Mammalian cell |
| CSB-MP002061HU-WD | Recombinant Human Kit ligand (KITLG)，Partial (Active) | Mammalian cell |
KITLG ELISA Kit
KITLG ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04718h | Human Stem cell factor/mast cell growth factor,SCF/MGF ELISA kit | serum, plasma, cell culture supernates | 0.11 ng/mL |
KITLG ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04719m | Mouse Stem cell factor/mast cell growth factor,SCF/MGF ELISA kit | serum, plasma, tissue homogenates | 0.78 pg/mL |
KITLG ELISA Kit for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04720r | Rat Stem cell factor/mast cell growth factor,SCF/MGF ELISA kit | serum, plasma, tissue homogenates | 1.56 pg/mL |
