ITGA2
ITGA2，即整合素α2亞基，別名CD49b、GPIa、HPA-5、VLA-2，是一種150 kDa的膜表面糖蛋白，在多種細(xì)胞類型中表達(dá)，如血小板、腸上皮細(xì)胞、NK細(xì)胞、上皮細(xì)胞和活化T細(xì)胞等。
ITGA2的作用機(jī)制是與CD29（整合素β1）非共價(jià)結(jié)合形成異質(zhì)二聚體VLA-2，即血小板糖蛋白Ia/IIa (CD49b/CD29)，介導(dǎo)成熟巨核細(xì)胞和血小板與膠原之間的粘附。ITGA2在細(xì)胞外基質(zhì)細(xì)胞粘附中起著重要作用，參與細(xì)胞粘附、遷移、增殖和信號(hào)傳導(dǎo)等過程，對(duì)維持組織結(jié)構(gòu)和功能完整性至關(guān)重要。異常的ITGA2表達(dá)與多種疾病相關(guān)，包括多種動(dòng)脈疾病、血小板疾病、糖尿病等。
熱銷產(chǎn)品
Recombinant Human Integrin alpha-2 (ITGA2), partial (CSB-EP011864HUb0)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
驗(yàn)證數(shù)據(jù)
Western Blot analysis of 3T3 cells using Integrin α2 Polyclonal Antibody
Western Blot analysis of NIH-3T3 cells using Integrin α2 Polyclonal Antibody
Human Integrin alpha-2(ITGA2) ELISA kit (CSB-EL011864HU)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL011864HU
規(guī)格：96T/48T
靈敏度：0.058 ng/mL
檢測(cè)范圍：0.235 ng/mL-15 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
ITGA2 Antibodies
ITGA2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA006197 | ITGA2 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA938467 | ITGA2 Antibody | Human | ELISA,WB,IHC |
| CSB-PA079340 | ITGA2 Antibody | Human | ELISA,WB,IHC |
| CSB-PA011864LA01HU | ITGA2 Antibody | Human | ELISA, IHC, IF |
| CSB-PA011864LD01HU | ITGA2 Antibody, Biotin conjugated | Human | ELISA |
ITGA2 Proteins
ITGA2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011864HU | Recombinant Human Integrin alpha-2 (ITGA2), partial | Yeast |
| CSB-EP011864HU | Recombinant Human Integrin alpha-2 (ITGA2), partial | E.coli |
| CSB-BP011864HU CSB-MP011864HU CSB-EP011864HU-B |
Recombinant Human Integrin alpha-2 (ITGA2), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP011864HUb0 | Recombinant Human Integrin alpha-2 (ITGA2), partial | E.coli |
ITGA2 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011864BO CSB-EP011864BO CSB-BP011864BO CSB-MP011864BO CSB-EP011864BO-B |
Recombinant Bovine Integrin alpha-2 (ITGA2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ITGA2 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP714022MO CSB-EP714022MO CSB-BP714022MO CSB-MP714022MO CSB-EP714022MO-B |
Recombinant Mouse Integrin alpha-2 (Itga2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ITGA2 ELISA Kit
ITGA2 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL011864HU | Human Integrin alpha-2(ITGA2) ELISA kit | serum, plasma, tissue homogenates | 0.058 ng/mL |
