IKZF3
IKZF3，即IKAROS家族鋅指蛋白3，別名AIO、IMD84、AIOLOS、ZNFN1A3。IKZF3作為轉錄因子，通過其鋅指結構域與DNA結合，參與淋巴細胞的發育和調節B淋巴細胞的增殖和分化。IKZF3能夠參與染色質重塑，形成Ikaros同二聚體、Ikaros/Aiolos異二聚體和Aiolos同二聚體，從而調節基因表達。IKZF3在多種造血和免疫細胞中發揮多效性作用，尤其在B淋巴細胞的分化和成熟中占主導地位，介導激活B淋巴細胞對刺激的反應和B細胞增殖。IKZF3的功能紊亂與惡性腫瘤、自身免疫病和免疫缺陷等多種疾病的病理過程相關，其在多發性骨髓瘤中過度表達，導致惡性漿細胞的大量增殖。
熱銷產品
IKZF3 Antibody (CSB-PA892336DSR1HU)
驗證數據
Western blot
All lanes: Zinc finger protein Aiolos antibody at 8μg/ml + HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 59, 52, 54, 30, 48, 50, 55, 42, 36, 33, 43, 31 kDa
Observed band size: 59 kDa
Human Zinc finger protein Aiolos(IKZF3) ELISA kit (CSB-EL011577HU)
驗證數據
貨號：CSB-EL011577HU
規格：96T/48T
靈敏度：6.25 pg/mL
檢測范圍：25 pg/mL-1600 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
IKZF3 Antibodies
IKZF3 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA011577GA01HU | IKZF3 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA892336DSR1HU | IKZF3 Antibody | Human | ELISA, WB |
| CSB-PA970658 | IKZF3 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA003007 | IKZF3 Antibody | Human,Mouse | WB, ELISA |
| CSB-PA192244 | IKZF3 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA577111 | IKZF3 Antibody | Human,Mouse | ELISA,IHC |
IKZF3 Proteins
IKZF3 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP892336HU CSB-EP892336HU CSB-BP892336HU CSB-MP892336HU CSB-EP892336HU-B |
Recombinant Human Zinc finger protein Aiolos (IKZF3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IKZF3 ELISA Kit
IKZF3 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL011577HU | Human Zinc finger protein Aiolos(IKZF3) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 6.25 pg/mL |
