IKZF1
IKZF1，即IKAROS家族鋅指蛋白1，別名IK1、LYF1、hIk-1、IKAROS、PPP1R92、PRO0758、ZNFN1A1。IKZF1屬于IKAROS家族轉(zhuǎn)錄因子，具有多個(gè)鋅指結(jié)構(gòu)域，參與染色質(zhì)重塑和淋巴細(xì)胞分化的調(diào)控。IKZF1與DNA結(jié)合以及與其他核蛋白的相互作用，能夠作為轉(zhuǎn)錄激活因子或抑制因子，調(diào)節(jié)靶基因的表達(dá)。IKZF1在多種造血和免疫細(xì)胞的發(fā)育中發(fā)揮重要作用，尤其是在B細(xì)胞和T細(xì)胞的分化、增殖中起關(guān)鍵作用。IKZF1的功能紊亂與多種疾病相關(guān)，包括惡性腫瘤、自身免疫病和免疫缺陷等，其缺失或功能失調(diào)與急性淋巴細(xì)胞白血病（ALL）和急性髓系白血病有關(guān)。
熱銷產(chǎn)品
Recombinant Human DNA-binding protein Ikaros (IKZF1) (CSB-EP621668HU)
驗(yàn)證數(shù)據(jù)
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP621668HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) IKZF1.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP621668HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) IKZF1.
IKZF1 Recombinant Monoclonal Antibody (CSB-RA266291A0HU)
驗(yàn)證數(shù)據(jù)
Overlay Peak curve showing Jurkat cells stained with CSB-RA266291A0HU (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1μg/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4℃.Control antibody (green line) was rabbit IgG (1μg/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
IKZF1 Antibodies
IKZF1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA011575GA01HU | IKZF1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA621668LA01HU | IKZF1 Antibody | Human | ELISA |
| CSB-PA621668LB01HU | IKZF1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA621668LC01HU | IKZF1 Antibody, FITC conjugated | Human | |
| CSB-PA621668LD01HU | IKZF1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA621668HA01HU | IKZF1 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA621668HB01HU | IKZF1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA621668HC01HU | IKZF1 Antibody, FITC conjugated | Human | |
| CSB-PA621668HD01HU | IKZF1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA266291A0HU | IKZF1 Recombinant Monoclonal Antibody | Human | ELISA, FC |
IKZF1 Proteins
IKZF1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011575MO CSB-EP011575MO CSB-BP011575MO CSB-MP011575MO CSB-EP011575MO-B |
Recombinant Mouse DNA-binding protein Ikaros (Ikzf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IKZF1 Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011575CH CSB-EP011575CH CSB-BP011575CH CSB-MP011575CH CSB-EP011575CH-B |
Recombinant Chicken DNA-binding protein Ikaros (IKZF1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IKZF1 Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011575OEI CSB-EP011575OEI CSB-BP011575OEI CSB-MP011575OEI CSB-EP011575OEI-B |
Recombinant Oncorhynchus mykiss DNA-binding protein Ikaros (ikzf1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IKZF1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP621668HU CSB-BP621668HU CSB-MP621668HU CSB-EP621668HU-B |
Recombinant Human DNA-binding protein Ikaros (IKZF1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP621668HU | Recombinant Human DNA-binding protein Ikaros (IKZF1) | E.coli |
