HUS1
Checkpoint protein HUS1 is a protein in humans that is encoded by HUS1 gene. Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates.
HUS1 Antibodies
HUS1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA010909LA01HU | HUS1 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA010909GA01HU | HUS1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
HUS1 Proteins
HUS1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP010909HU CSB-BP010909HU CSB-MP010909HU CSB-EP010909HU-B |
Recombinant Human Checkpoint protein HUS1 (HUS1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP010909HU | Recombinant Human Checkpoint protein HUS1 (HUS1), partial | E.coli |
HUS1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP010909SXV CSB-EP010909SXV CSB-BP010909SXV CSB-MP010909SXV CSB-EP010909SXV-B |
Recombinant Schizosaccharomyces pombe Checkpoint protein hus1 (hus1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
HUS1 Proteins for Dictyostelium discoideum (Slime mold)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP687659DKK CSB-EP687659DKK CSB-BP687659DKK CSB-MP687659DKK CSB-EP687659DKK-B |
Recombinant Dictyostelium discoideum Checkpoint protein hus1 homolog (hus1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
HUS1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP804843MO CSB-EP804843MO CSB-BP804843MO CSB-MP804843MO CSB-EP804843MO-B |
Recombinant Mouse Checkpoint protein HUS1 (Hus1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
