GPR55
GPR55，即G蛋白偶聯(lián)受體55，別名LPI1、GPR55、PSIGPR53。GPR55由人類GPR55基因編碼，該基因位于2號染色體的q37.1區(qū)域。GPR55是一種G蛋白偶聯(lián)受體，可能通過激活多種信號轉(zhuǎn)導(dǎo)通路參與多種生理和病理過程。它被激活的配體包括植物性大麻素、內(nèi)源性大麻素以及溶血磷脂酰肌醇（LPI）。GPR55與情緒、運動、認知、學習和記憶等生理功能相關(guān)，同時也與大麻素的作用以及藥物濫用有關(guān)。GPR55還可能成為治療炎癥、疼痛、糖尿病、帕金森病、神經(jīng)病理性疼痛和癌癥的新潛在藥物靶點。研究表明，GPR55在調(diào)節(jié)焦慮樣行為、海馬神經(jīng)發(fā)生以及神經(jīng)保護方面發(fā)揮作用。
熱銷產(chǎn)品
GPR55 Antibody (CSB-PA009820OA01HU)
驗證數(shù)據(jù)
IHC image of CSB-PA009820OA01HU diluted at 1:100 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
GPR55 Antibodies
GPR55 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA009820OA01HU | GPR55 Antibody | Human | ELISA, IHC |
| CSB-PA009820OB01HU | GPR55 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA009820OC01HU | GPR55 Antibody, FITC conjugated | Human | |
| CSB-PA009820OD01HU | GPR55 Antibody, Biotin conjugated | Human | ELISA |
GPR55 Proteins
GPR55 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP661042MO1 CSB-EP661042MO1 CSB-BP661042MO1 CSB-MP661042MO1 CSB-EP661042MO1-B |
Recombinant Mouse G-protein coupled receptor 55 (Gpr55), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF661042MO | Recombinant Mouse G-protein coupled receptor 55 (Gpr55) | in vitro E.coli expression system |
