GPER1
G-protein coupled estrogen receptor 1 is a protein in humans that is encoded by GPER1 gene. G-protein coupled estrogen receptor that binds to 17-beta-estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Stimulates cAMP production, calcium mobilization and tyrosine kinase Src inducing the release of heparin-bound epidermal growth factor (HB-EGF) and subsequent transactivation of the epidermal growth factor receptor (EGFR), activating downstream signaling pathways such as PI3K/Akt and ERK/MAPK. Mediates pleiotropic functions among others in the cardiovascular, endocrine, reproductive, immune and central nervous systems. Has a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a RAMP3-dependent manner. Regulates arterial blood pressure by stimulating vasodilation and reducing vascular smooth muscle and microvascular endothelial cell proliferation.
GPER1 Antibodies
GPER1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA934518 | GPER1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA859933LA01HU | GPER1 Antibody | Human, Mouse | ELISA, WB, IHC, IF |
| CSB-PA859933LB01HU | GPER1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA859933LC01HU | GPER1 Antibody, FITC conjugated | Human | |
| CSB-PA859933LD01HU | GPER1 Antibody, Biotin conjugated | Human | ELISA |
GPER1 Proteins
GPER1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP009713RA1 CSB-EP009713RA1 CSB-BP009713RA1 CSB-MP009713RA1 CSB-EP009713RA1-B |
Recombinant Rat G-protein coupled estrogen receptor 1 (Gper), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009713RA | Recombinant Rat G-protein coupled estrogen receptor 1 (Gper) | in vitro E.coli expression system |
GPER1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP805929MO1 CSB-EP805929MO1 CSB-BP805929MO1 CSB-MP805929MO1 CSB-EP805929MO1-B |
Recombinant Mouse G-protein coupled estrogen receptor 1 (Gper), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF805929MO | Recombinant Mouse G-protein coupled estrogen receptor 1 (Gper) | in vitro E.coli expression system |
GPER1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP859933HU1 CSB-EP859933HU1 CSB-BP859933HU1 CSB-MP859933HU1 CSB-EP859933HU1-B |
Recombinant Human G-protein coupled estrogen receptor 1 (GPER1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF859933HU | Recombinant Human G-protein coupled estrogen receptor 1 (GPER1) | in vitro E.coli expression system |
