GKN1
GKN1，全稱為Gastrokine-1，是一種在人類胃黏膜中表達(dá)的蛋白質(zhì)，常見(jiàn)別名包括18 kDa antrum mucosa protein和CA11。該蛋白主要在胃黏膜上皮細(xì)胞中表達(dá)，參與維持胃黏膜的完整性和更新。研究表明，GKN1蛋白可能通過(guò)促進(jìn)黏膜細(xì)胞增殖和遷移，以及穩(wěn)定緊密連接蛋白來(lái)保護(hù)胃腸黏膜。此外，GKN1蛋白的表達(dá)水平在胃癌組織中顯著下調(diào)，提示其可能作為胃癌的診斷和預(yù)后指標(biāo)。已有研究將GKN1蛋白與胃癌患者的預(yù)后情況相結(jié)合，發(fā)現(xiàn)其低表達(dá)與不良預(yù)后相關(guān)。目前，針對(duì)GKN1蛋白的研究主要集中在探索其作為胃癌診斷和治療靶點(diǎn)的潛力。例如，開(kāi)發(fā)針對(duì)GKN1蛋白的檢測(cè)試劑盒，以及尋找能夠調(diào)節(jié)GKN1蛋白表達(dá)或活性的藥物，以期用于胃癌的早期診斷和個(gè)性化治療。
熱銷產(chǎn)品
Recombinant Human Gastrokine-1 (GKN1) (CSB-EP868309HUb1)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
GKN1 Antibodies
GKN1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA009469GA01HU | GKN1 Antibody | Human | ELISA,WB,IHC |
| CSB-PA10589A0Rb | GKN1 Antibody | Human | ELISA |
| CSB-PA10589B0Rb | GKN1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA10589C0Rb | GKN1 Antibody, FITC conjugated | Human | |
| CSB-PA10589D0Rb | GKN1 Antibody, Biotin conjugated | Human | ELISA |
GKN1 Proteins
GKN1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-BP868309HU CSB-MP868309HU CSB-EP868309HU-B |
Recombinant Human Gastrokine-1 (GKN1) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP868309HU | Recombinant Human Gastrokine-1 (GKN1) | E.coli |
| CSB-MP868309HUc7 | Recombinant Human Gastrokine-1 (GKN1) | Mammalian cell |
| CSB-EP868309HUb1 | Recombinant Human Gastrokine-1 (GKN1) | E.coli |
| CSB-YP868309HU | Recombinant Human Gastrokine-1 (GKN1), partial | Yeast |
GKN1 ELISA Kit
GKN1 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL009469HU | Human Gastrokine-1(GKN1) ELISA kit | serum, plasma, tissue homogenates | 0.156 ng/mL |
