FZD8
FZD8，全稱(chēng)Frizzled class receptor 8，是一種屬于Frizzled家族的G蛋白偶聯(lián)受體，在人類(lèi)中編碼該蛋白的基因?yàn)镕ZD8。該蛋白常見(jiàn)別名包括FZ-8、hFZ8等。FZD8在多種組織中表達(dá)，尤其在神經(jīng)系統(tǒng)、心血管系統(tǒng)和骨骼系統(tǒng)中具有顯著功能。它通過(guò)其細(xì)胞外結(jié)構(gòu)域與Wnt配體結(jié)合，進(jìn)而激活下游信號(hào)傳導(dǎo)，影響細(xì)胞增殖、分化和組織穩(wěn)態(tài)。FZD8與多種疾病相關(guān)，如癌癥（結(jié)直腸癌、乳腺癌等）和發(fā)育障礙。近年來(lái)，F(xiàn)ZD8成為藥物研發(fā)的熱點(diǎn)靶點(diǎn)，研究人員開(kāi)發(fā)了針對(duì)FZD8的單克隆抗體和雙特異性抗體，用于阻斷Wnt信號(hào)通路，從而抑制腫瘤生長(zhǎng)。此外，F(xiàn)ZD8也被探索作為治療皮膚創(chuàng)面修復(fù)和再生的潛在靶點(diǎn)。
FZD8 Antibodies
FZD8 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA060239 | FZD8 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA617545 | FZD8 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA360153 | FZD8 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA880970LA01HU | FZD8 Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA880970LB01HU | FZD8 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA880970LC01HU | FZD8 Antibody, FITC conjugated | Human | |
| CSB-PA880970LD01HU | FZD8 Antibody, Biotin conjugated | Human | ELISA |
FZD8 Proteins
FZD8 Proteins for Xenopus laevis (African clawed frog)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP009111XBE1 CSB-EP009111XBE1 CSB-BP009111XBE1 CSB-MP009111XBE1 CSB-EP009111XBE1-B |
Recombinant Xenopus laevis Frizzled-8 (fzd8), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009111XBE | Recombinant Xenopus laevis Frizzled-8 (fzd8) | in vitro E.coli expression system |
FZD8 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP677711RA1 CSB-EP677711RA1 CSB-BP677711RA1 CSB-MP677711RA1 CSB-EP677711RA1-B |
Recombinant Rat Frizzled-8 (Fzd8), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF677711RA | Recombinant Rat Frizzled-8 (Fzd8) | in vitro E.coli expression system |
FZD8 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP726733MO1 CSB-EP726733MO1 CSB-BP726733MO1 CSB-MP726733MO1 CSB-EP726733MO1-B |
Recombinant Mouse Frizzled-8 (Fzd8), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF726733MO | Recombinant Mouse Frizzled-8 (Fzd8) | in vitro E.coli expression system |
FZD8 Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP878007CH1 CSB-EP878007CH1 CSB-BP878007CH1 CSB-MP878007CH1 CSB-EP878007CH1-B |
Recombinant Chicken Frizzled-8 (FZD8), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF878007CH | Recombinant Chicken Frizzled-8 (FZD8) | in vitro E.coli expression system |
FZD8 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP880970HU1 CSB-EP880970HU1 CSB-BP880970HU1 CSB-MP880970HU1 CSB-EP880970HU1-B |
Recombinant Human Frizzled-8 (FZD8), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF880970HU | Recombinant Human Frizzled-8 (FZD8) | in vitro E.coli expression system |
