FOXA2
FOXA2，即叉頭框蛋白A2，別名HNF3B、TCF3B。FOXA2屬于叉頭類(lèi)轉(zhuǎn)錄因子家族，具有高度保守的翼狀螺旋結(jié)構(gòu)域，能夠以單體形式結(jié)合在靶基因啟動(dòng)子區(qū)的DNA序列上。FOXA2通過(guò)與染色質(zhì)的相互作用，改變?nèi)旧|(zhì)局部結(jié)構(gòu)來(lái)調(diào)控基因表達(dá)，被稱為“先鋒因子”。FOXA2在多種生物學(xué)過(guò)程中起關(guān)鍵作用，包括胚胎發(fā)育、細(xì)胞分化及疾病發(fā)生過(guò)程。FOXA2還參與調(diào)節(jié)肝臟功能基因的表達(dá)，包括血漿蛋白、載脂蛋白、凝血因子以及葡萄糖、脂肪酸、氨基酸代謝中的關(guān)鍵代謝酶，參與肝臟發(fā)育、器官形成、代謝和穩(wěn)態(tài)維持等多種生物學(xué)過(guò)程。FOXA2的表達(dá)異常與多種疾病相關(guān)，包括肝癌、肺癌、胰腺癌、胃癌、甲狀腺癌和大腸癌。
熱銷(xiāo)產(chǎn)品
驗(yàn)證數(shù)據(jù)
Western blot analysis of extracts from 293, HT29, HepG2 cells using FoxA2(HNF3b) Antibody.
FOXA2 Antibodies
FOXA2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA146585 | FOXA2 Antibody | Human | ELISA,WB |
| CSB-PA927484 | FOXA2 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA167678 | FOXA2 Antibody | Human,Mouse,Rat | ELISA,WB |
FOXA2 Proteins
FOXA2 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP008795MO CSB-EP008795MO CSB-BP008795MO CSB-MP008795MO CSB-EP008795MO-B |
Recombinant Mouse Hepatocyte nuclear factor 3-beta (Foxa2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FOXA2 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP008795RA CSB-EP008795RA CSB-BP008795RA CSB-MP008795RA CSB-EP008795RA-B |
Recombinant Rat Hepatocyte nuclear factor 3-beta (Foxa2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FOXA2 Proteins for Oryzias latipes (Medaka fish) (Japanese ricefish)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP008795OFH CSB-EP008795OFH CSB-BP008795OFH CSB-MP008795OFH CSB-EP008795OFH-B |
Recombinant Oryzias latipes Hepatocyte nuclear factor 3-beta (foxa2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FOXA2 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP742473XBF CSB-EP742473XBF CSB-BP742473XBF CSB-MP742473XBF CSB-EP742473XBF-B |
Recombinant Xenopus tropicalis Forkhead box protein A2 (foxa2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FOXA2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP897462HU CSB-EP897462HU CSB-BP897462HU CSB-MP897462HU CSB-EP897462HU-B |
Recombinant Human Hepatocyte nuclear factor 3-beta (FOXA2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
