FABP5
FABP5，即脂肪酸結(jié)合蛋白5，是一種廣泛存在于多種組織中的脂質(zhì)伴侶蛋白。它參與調(diào)控脂肪酸的攝取、轉(zhuǎn)運(yùn)、代謝以及炎癥反應(yīng)等多種生物學(xué)過程。FABP5的作用機(jī)制涉及與長鏈不飽和脂肪酸的結(jié)合，進(jìn)而影響細(xì)胞內(nèi)的脂質(zhì)代謝和信號(hào)傳導(dǎo)。特別是在氧化應(yīng)激狀態(tài)下，F(xiàn)ABP5可以通過谷胱甘肽化修飾，促進(jìn)其核轉(zhuǎn)位，激活PPARβ/δ信號(hào)通路，抑制巨噬細(xì)胞炎癥，對急性肺損傷等炎癥性疾病具有保護(hù)作用。此外，F(xiàn)ABP5還通過調(diào)節(jié)PPARγ信號(hào)通路影響巨噬細(xì)胞的M2極化，進(jìn)而參與過敏性哮喘等免疫調(diào)節(jié)過程。FABP5的功能異常與多種疾病包括癌癥、炎癥性疾病和代謝性疾病等有關(guān)，是重要的疾病治療靶點(diǎn)。
熱銷產(chǎn)品
Recombinant Human Fatty acid-binding protein 5 (FABP5) (CSB-EP007946HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Human Fatty acid-binding protein, epidermal(FABP5) ELISA kit (CSB-EL007946HU)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL007946HU
規(guī)格：96T/48T
靈敏度：0.195 ng/mL
檢測范圍：0.78 ng/mL-50 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
FABP5 Antibodies
FABP5 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA007946GA01HU | FABP5 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA007946ESR1HU | FABP5 Antibody | Human | ELISA, WB |
FABP5 Proteins
FABP5 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP007946RA CSB-EP007946RA CSB-BP007946RA CSB-MP007946RA CSB-EP007946RA-B |
Recombinant Rat Fatty acid-binding protein, epidermal (Fabp5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FABP5 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP007946BO CSB-EP007946BO CSB-BP007946BO CSB-MP007946BO CSB-EP007946BO-B |
Recombinant Bovine Fatty acid-binding protein, epidermal (FABP5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FABP5 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-EP007946HUe0 | Recombinant Human Fatty acid-binding protein (FABP5) | E.coli |
| CSB-EP007946HU | Recombinant Human Fatty acid-binding protein 5 (FABP5) | E.coli |
FABP5 ELISA Kit
FABP5 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL007946HU | Human Fatty acid-binding protein, epidermal(FABP5) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 0.195 ng/mL |
