DKK3
DKK3，即DickkopfWNT信號(hào)通路抑制因子3，別名Dickkopf-3。它是一種分泌性糖蛋白，屬于DKK相關(guān)蛋白家族成員之一。DKK3主要通過(guò)調(diào)節(jié)經(jīng)典Wnt/β-catenin信號(hào)通路發(fā)揮作用，具有調(diào)控組織發(fā)育、凋亡、增殖、代謝和免疫反應(yīng)等多種重要生物學(xué)功能。DKK3在心臟疾病、腫瘤、免疫調(diào)節(jié)通路、神經(jīng)發(fā)生及代謝性疾病方面均有研究，尤其在心臟疾病及腫瘤等方面，DKK3的相關(guān)生物學(xué)功能及其與人類疾病的相關(guān)性使其可以作為相關(guān)人類疾病診斷以及治療的一個(gè)重要分子標(biāo)志物。DKK3在心血管疾病包括心力衰竭和腎臟疾病中的作用被特別關(guān)注，研究表明，DKK3在心臟可能具有保護(hù)作用，但在腎臟可能具有不利影響。DKK3作為新興的生物標(biāo)志物，其在血漿和尿液中的水平與心血管疾病和腎臟疾病的發(fā)生發(fā)展有關(guān)。
熱銷產(chǎn)品
驗(yàn)證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA037884(DKK3 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA037884(DKK3 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal brain tissue, Primary antibody: CSB-PA037884(DKK3 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
DKK3 Antibodies
DKK3 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA006922GA01HU | DKK3 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA694792 | DKK3 Antibody | Human | ELISA,WB |
| CSB-PA008861 | DKK3 Antibody | Human,Mouse | WB, ELISA |
| CSB-PA274333 | DKK3 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA037884 | DKK3 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA890660LA01HU | DKK3 Antibody | Human | ELISA |
| CSB-PA890660LC01HU | DKK3 Antibody, FITC conjugated | Human |
DKK3 Proteins
DKK3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP890660HU CSB-EP890660HU CSB-BP890660HU CSB-MP890660HU CSB-EP890660HU-B |
Recombinant Human Dickkopf-related protein 3 (DKK3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DKK3 ELISA Kit
DKK3 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E13607h | Human Dickkopf 3,DKK3 ELISA Kit | serum, plasma, tissue homogenates | 7.8 pg/mL |
