CLDN3
CLDN3（Claudin-3）是一種細(xì)胞間緊密連接的蛋白質(zhì)，參與細(xì)胞的黏附和信號傳遞。它主要在上皮組織中表達(dá)，并參與調(diào)節(jié)細(xì)胞的極性、滲透性和細(xì)胞間通訊等功能。此外，CLDN3在許多癌癥中的表達(dá)升高，包括卵巢癌、乳腺癌、胃癌、前列腺癌等。許多研究表明，CLDN3可以作為腫瘤診斷和治療的潛在靶點(diǎn)。一些針對CLDN3的治療策略，例如抗CLDN3單克隆抗體、siRNA和小分子化合物，已被開發(fā)，并在臨床試驗(yàn)中得到驗(yàn)證。因此，CLDN3的研究和開發(fā)具有重要的臨床意義，對于癌癥治療和預(yù)防具有重要的潛在價(jià)值。
更多相關(guān)閱讀：CLDN3，極為關(guān)鍵的緊密連接蛋白，Claudins家族再添藥物靶點(diǎn)！
熱銷產(chǎn)品
Recombinant Human Claudin-3(CLDN3)-VLPs (Active)(CSB-MP005505HU)
驗(yàn)證數(shù)據(jù)
The high specifity was validated by western blot. (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Immobilized Human CLDN3 at 10μg/mL can bind Anti-CLDN3 recombinant antibody (CSB-RA005505MA1HU), the EC50?is 23.62-34.37 ng/mL.VLPs (CSB-MP3838) is negative control.
CLDN3 Antibodies
CLDN3 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA005505GA01HU | CLDN3 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA193301 | CLDN3 Antibody | Human | ELISA,WB,IHC,IF |
| CSB-PA001661 | CLDN3 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA007223 | Phospho-CLDN3 (Y219) Antibody | Human | WB, IHC, ELISA |
| CSB-PA007225 | CLDN3 Antibody | Human | WB, IHC, ELISA |
| CSB-PA561954 | CLDN3 Antibody | Human | ELISA,WB,IHC |
| CSB-PA068230 | CLDN3 Antibody | Human | ELISA,IHC |
| CSB-PA13119A0Rb | CLDN3 Antibody | Human | ELISA, WB, IHC |
| CSB-PA13119B0Rb | CLDN3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA13119D0Rb | CLDN3 Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA005505MA1HU | CLDN3 Recombinant Monoclonal Antibody | Human | ELISA |
CLDN3 Proteins
CLDN3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP005505HU1 CSB-EP005505HU1 CSB-BP005505HU1 CSB-MP005505HU1 CSB-EP005505HU1-B |
Recombinant Human Claudin-3 (CLDN3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF005505HU | Recombinant Human Claudin-3 (CLDN3) | in vitro E.coli expression system |
| CSB-EP005505HU1a6 | Recombinant Human Claudin-3 (CLDN3), partial | E.coli |
| CSB-MP005505HU | Recombinant Human Claudin-3 (CLDN3)-VLPs (Active) | Mammalian cell |
CLDN3 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP723578RA1 CSB-EP723578RA1 CSB-BP723578RA1 CSB-MP723578RA1 CSB-EP723578RA1-B |
Recombinant Rat Claudin-3 (Cldn3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF723578RA | Recombinant Rat Claudin-3 (Cldn3) | in vitro E.coli expression system |
CLDN3 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP748461BO1 CSB-EP748461BO1 CSB-BP748461BO1 CSB-MP748461BO1 CSB-EP748461BO1-B |
Recombinant Bovine Claudin-3 (CLDN3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF748461BO | Recombinant Bovine Claudin-3 (CLDN3) | in vitro E.coli expression system |
CLDN3 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP842554DO1 CSB-EP842554DO1 CSB-BP842554DO1 CSB-MP842554DO1 CSB-EP842554DO1-B |
Recombinant Dog Claudin-3 (CLDN3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF842554DO | Recombinant Dog Claudin-3 (CLDN3) | in vitro E.coli expression system |
CLDN3 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP897449MO1 CSB-EP897449MO1 CSB-BP897449MO1 CSB-MP897449MO1 CSB-EP897449MO1-B |
Recombinant Mouse Claudin-3 (Cldn3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF897449MO | Recombinant Mouse Claudin-3 (Cldn3) | in vitro E.coli expression system |
CLDN3 ELISA Kit
CLDN3 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL005505HU | Human Claudin-3(CLDN3) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 6.25 pg/mL |
