CFH
CFH，即補(bǔ)體因子H，別名HUS、FHL1、ARMS1、ARMD4等。它是由人體肝臟及一些其他細(xì)胞產(chǎn)生的一種血清糖蛋白，主要在補(bǔ)體系統(tǒng)的調(diào)節(jié)中發(fā)揮作用。CFH的作用機(jī)制主要是通過與C3b結(jié)合，抑制補(bǔ)體旁路途徑C3轉(zhuǎn)化酶的形成，促進(jìn)C3轉(zhuǎn)化酶的分解，從而控制補(bǔ)體激活，保護(hù)宿主細(xì)胞免受補(bǔ)體的破壞。CFH的生物學(xué)意義非常廣泛，它不僅在免疫防御中保護(hù)自身細(xì)胞，防止補(bǔ)體系統(tǒng)的過度激活，還涉及到多種疾病的發(fā)生發(fā)展，如年齡相關(guān)性黃斑變性（AMD）、某些腎臟疾病和心血管疾病等。CFH基因的突變或異常表達(dá)與這些疾病的發(fā)生有密切關(guān)系。
熱銷產(chǎn)品
Recombinant Human Complement factor H (CFH), partial (CSB-EP005273HU(F1))
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CFH Antibody (CSB-PA005273ESR2HU)
驗(yàn)證數(shù)據(jù)
Western blot
All lanes: CFH antibody at 3µg/ml + human serum
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 140, 52 kDa
Observed band size: 140 kDa
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA005273ESR2HU at dilution of 1:100
CFH Antibodies
CFH for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA005273GA01HU | CFH Antibody | Human | ELISA,WB |
| CSB-PA005273ESR2HU | CFH Antibody | Human | ELISA, WB, IHC |
CFH Proteins
CFH Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP005273HU(F1) CSB-BP005273HU(F1) CSB-EP005273HU(F1)-B |
Recombinant Human Complement factor H (CFH), partial | Yeast Baculovirus In Vivo Biotinylation in E.coli |
| CSB-EP005273HU(F1) | Recombinant Human Complement factor H (CFH), partial | E.coli |
| CSB-MP005273HU(F1) | Recombinant Human Complement factor H (CFH), partial | Mammalian cell |
| CSB-MP005273HU(F1)d9 | Recombinant Human Complement factor H (CFH), partial | Mammalian cell |
CFH Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP005273MO CSB-EP005273MO CSB-BP005273MO CSB-MP005273MO CSB-EP005273MO-B |
Recombinant Mouse Complement factor H (Cfh), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CFH Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP005273BO CSB-EP005273BO CSB-BP005273BO CSB-MP005273BO CSB-EP005273BO-B |
Recombinant Bovine Complement factor H (CFH), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CFH ELISA Kit
CFH ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08931h | Human complement factor H,CFH ELISA Kit | serum, plasma, tissue homogenates | 7.8 ng/ml |
CFH ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08933m | Mouse complement factor H,CFH ELISA Kit | serum, plasma, tissue homogenates | 7.81 ng/mL |
