CADM1
CADM1（Cell Adhesion Molecule 1）也被稱為SynCAM1（Synaptic Cell Adhesion Molecule 1）;參與多種生物學過程和疾病發生發展。 ADM1的胞外結構域包括一個N-末端信號序列、三個Ig-like結構域和一個C-末端結構域，其中第一個Ig-like結構域參與了細胞間的黏附和信號轉導。CADM1的細胞內結構域包括一個短的胞內區域和一個長的胞內區域，前者含有一個肽鍵酶切位點和幾個磷酸化位點，后者則包含多個蛋白質相互作用位點和信號調節結構域 它在神經元、免疫細胞、腫瘤等細胞中表達，并通過其胞外結構域和細胞內信號通路影響細胞間的黏附、遷移、增殖和凋亡等生物學行為。
更多相關閱讀：CADM1/TSLC1：免疫球蛋白超家族黏附分子，一種新的TSG腫瘤抑制基因！
熱銷產品
Recombinant Mouse Cell adhesion molecule 1(Cadm1),partial (Active) CSB-MP004425MO
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse CADM1 at 2μg/mL can bind Mouse CRTAM (CSB-MP614820MO)， the EC50?is 52.61-92.92 ng/mL.?
CADM1 Antibodies
CADM1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA004425GA01HU | CADM1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA004425ESR2HU | CADM1 Antibody | Human | ELISA, IHC |
| CSB-PA112392 | CADM1 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA004340 | CADM1 Antibody | Human,Mouse | WB, IF, ELISA |
CADM1 Proteins
CADM1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004425MO CSB-EP004425MO CSB-BP004425MO CSB-EP004425MO-B |
Recombinant Mouse Cell adhesion molecule 1 (Cadm1), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP004425MO | Recombinant Mouse Cell adhesion molecule 1 (Cadm1), partial (Active) | Mammalian cell |
CADM1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004425HU CSB-EP004425HU CSB-BP004425HU CSB-EP004425HU-B |
Recombinant Human Cell adhesion molecule 1 (CADM1), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP004425HU | Recombinant Human Cell adhesion molecule 1 (CADM1), partial (Active) | Mammalian cell |
| CSB-MP004425HUd9 | Recombinant Human Cell adhesion molecule 1 (CADM1), partial | Mammalian cell |
