ASPA
ASPA，即天冬氨酸酶，它是一種在生物體內(nèi)具有多種功能的蛋白質(zhì) 。ASPA由日本國際熱傳導(dǎo)株式會社的研究人員于1975年發(fā)現(xiàn)，分子量為21.1 kDa，由兩個等量的多肽鏈組成，包含10個氨基酸 。它在細胞內(nèi)參與促進細胞增殖、誘導(dǎo)細胞凋亡、調(diào)節(jié)細胞周期和參與細胞信號傳遞等多種生物學(xué)過程 。在腫瘤研究中，ASPA被用作藥物靶點，能夠與腫瘤細胞中的蛋白質(zhì)相互作用，抑制腫瘤細胞的生長和擴散 。ASPA在藥物發(fā)現(xiàn)中具有廣泛的應(yīng)用，可以作為治療癌癥的藥物靶點，例如抑制ASPA活性的藥物可以抑制癌細胞的生長和擴散 。此外，ASPA還可以作為生物標志物，用于檢測疾病的程度和治療效果 。在生物學(xué)意義上，ASPA的活性和表達水平與多種疾病的發(fā)生發(fā)展密切相關(guān)，是醫(yī)學(xué)研究和治療中的一個重要靶點。
熱銷產(chǎn)品
Recombinant Human Aspartoacylase (ASPA) (CSB-YP002223HU)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
驗證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA790667(ASPA Antibody) at dilution 1/80, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human lymphoma tissue using CSB-PA790667(ASPA Antibody) at dilution 1/80, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse kidney tissue, human fetal kidney tissue, Primary antibody: CSB-PA790667(ASPA Antibody) at dilution 1/1400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second
ASPA Antibodies
ASPA for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA002223GA01HU | ASPA Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA790667 | ASPA Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA075666 | ASPA Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
ASPA Proteins
ASPA Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP002223HU | Recombinant Human Aspartoacylase (ASPA) | Yeast |
| CSB-EP002223HU | Recombinant Human Aspartoacylase (ASPA) | E.coli |
| CSB-BP002223HU | Recombinant Human Aspartoacylase (ASPA) | Baculovirus |
| CSB-MP002223HU | Recombinant Human Aspartoacylase (ASPA) | Mammalian cell |
