ASGR1
ASGR1，即肝素結(jié)合生長因子相關(guān)受體1，別名肝素結(jié)合蛋白1（HBP1）、肝素結(jié)合生長因子受體（HBGR）。ASGR1是一種主要表達(dá)在肝臟的細(xì)胞表面受體，由人體細(xì)胞自身的基因編碼。它的作用機(jī)制涉及到與多種配體的結(jié)合，包括肝素結(jié)合生長因子（HB-EGF）、肝素以及某些脂蛋白等。ASGR1通過與這些配體結(jié)合，參與調(diào)節(jié)細(xì)胞增殖、分化和遷移等過程，同時(shí)也在脂質(zhì)代謝和免疫反應(yīng)中發(fā)揮作用。ASGR1在生物學(xué)上的意義主要體現(xiàn)在其對肝臟功能的調(diào)節(jié)作用。它參與了肝臟對脂質(zhì)的攝取和代謝，特別是低密度脂蛋白（LDL）的清除。此外，ASGR1還與肝臟的再生能力有關(guān)，它通過促進(jìn)肝細(xì)胞的增殖來參與肝臟損傷后的修復(fù)過程。在病理狀態(tài)下，ASGR1的功能異常可能與某些肝臟疾病，如非酒精性脂肪肝病（NAFLD）和肝纖維化等有關(guān)。因此，ASGR1是肝病研究和治療中的一個(gè)潛在靶點(diǎn)。
熱銷產(chǎn)品
Recombinant Rat Asialoglycoprotein receptor 1 (Asgr1), partial (CSB-MP002207RA1)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ASGR1 Antibody (CSB-PA17469A0Rb)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA17469A0Rb at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA17469A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
ASGR1 Antibodies
ASGR1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA17469D0Rb | ASGR1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA17469B0Rb | ASGR1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA002207GA01HU | ASGR1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA17469C0Rb | ASGR1 Antibody, FITC conjugated | Human | |
| CSB-PA17469A0Rb | ASGR1 Antibody | Human | ELISA, IHC, IF |
| CSB-PA186229 | ASGR1 Antibody | Human | ELISA,WB,IHC |
ASGR1 Proteins
ASGR1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP002207MO | Recombinant Mouse Asialoglycoprotein receptor 1 (Asgr1), partial | Yeast |
| CSB-EP002207MO | Recombinant Mouse Asialoglycoprotein receptor 1 (Asgr1), partial | E.coli |
| CSB-CF002207MO(A4) | Recombinant Mouse Asialoglycoprotein receptor 1 (Asgr1) | in vitro E.coli expression system |
ASGR1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP002207HU CSB-BP002207HU CSB-MP002207HU CSB-EP002207HU-B |
Recombinant Human Asialoglycoprotein receptor 1 (ASGR1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP002207HU | Recombinant Human Asialoglycoprotein receptor 1 (ASGR1), partial | E.coli |
| CSB-CF002207HU(A4) | Recombinant Human Asialoglycoprotein receptor 1 (ASGR1) | in vitro E.coli expression system |
ASGR1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP002207RA1 CSB-EP002207RA1-B |
Recombinant Rat Asialoglycoprotein receptor 1 (Asgr1), partial | Yeast In Vivo Biotinylation in E.coli |
| CSB-CF002207RA | Recombinant Rat Asialoglycoprotein receptor 1 (Asgr1) | in vitro E.coli expression system |
| CSB-BP002207RA1 | Recombinant Rat Asialoglycoprotein receptor 1 (Asgr1), partial | Baculovirus |
| CSB-MP002207RA1 | Recombinant Rat Asialoglycoprotein receptor 1 (Asgr1), partial | Mammalian cell |
| CSB-EP002207RA1 | Recombinant Rat Asialoglycoprotein receptor 1 (Asgr1), partial | E.coli |
ASGR1 Proteins for Pongo abelii (Sumatran orangutan)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP002207PYX CSB-EP002207PYX CSB-BP002207PYX CSB-MP002207PYX CSB-EP002207PYX-B |
Recombinant Pongo abelii Asialoglycoprotein receptor 1 (ASGR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASGR1 ELISA Kit
ASGR1 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E09130h | Human asialoglyco protein receptor,ASGPR ELISA Kit | serum, plasma, tissue homogenates | 7.8 ng/mL |
