ARID1B
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF).
ARID1B Antibodies
ARID1B for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA210417 | ARID1B Antibody | Human,Rat | ELISA,WB,IF |
| CSB-PA040080 | ARID1B Antibody | Human,Rat | WB, IHC, IF, ELISA |
ARID1B Proteins
ARID1B Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP822780HU CSB-EP822780HU CSB-BP822780HU CSB-MP822780HU CSB-EP822780HU-B |
Recombinant Human AT-rich interactive domain-containing protein 1B (ARID1B), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
