ANXA1
ANXA1，即膜聯(lián)蛋白A1，別名lipocortinI。ANXA1由人類(lèi)ANXA1基因編碼，該基因定位于染色體9q24，含有13個(gè)外顯子和12個(gè)內(nèi)含子。ANXA1是一種鈣依賴的磷脂結(jié)合蛋白，屬于Annexins家族中的一員，其核心區(qū)域含有四個(gè)重復(fù)的“2型”鈣結(jié)合域基團(tuán)和一個(gè)N端結(jié)構(gòu)域。當(dāng)細(xì)胞質(zhì)中的ANXA1與鈣離子結(jié)合后，會(huì)向細(xì)胞膜轉(zhuǎn)移并與之結(jié)合，從而暴露N端結(jié)構(gòu)域，該結(jié)構(gòu)域是ANXA1的主要功能結(jié)構(gòu)域，主要通過(guò)與甲酰基肽受體FPR2結(jié)合發(fā)揮抗炎癥反應(yīng)和促進(jìn)溶解的作用。ANXA1在多種細(xì)胞生命活動(dòng)中發(fā)揮作用，包括抗炎癥反應(yīng)、細(xì)胞分化和增殖、細(xì)胞死亡信號(hào)調(diào)控、凋亡細(xì)胞吞噬清除等。
熱銷(xiāo)產(chǎn)品
Recombinant Human Annexin A1 (ANXA1), partial (CSB-EP001836HU1)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-RP134574h could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) ANX1.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-RP134574h could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) ANX1.
ANXA1 Recombinant Monoclonal Antibody (CSB-RA001836MA1HU)
驗(yàn)證數(shù)據(jù)
IHC image of CSB-RA001836MA1HU diluted at 1:30 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-Mouse IgG labeled by HRP and visualized using 0.05% DAB.
Overlay Peak curve showing MCF7 cells stained with CSB-RA001836MA1HU (red line) at 1:400. The cells were fixed in 4% formaldehyde (15min) and permeated by 0.2% TritonX-100 for 10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-Mouse IgG(H+L) at 1/200 dilution for 35 min at 4°C. Isotype control antibody (green line) was mouse IgG1 (1μg/1*106cells) used under the same conditions. Acquisition of >10,016 events was performed.
ANXA1 Antibodies
ANXA1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA001836GA01HU | ANXA1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA13457A0Rb | ANXA1 Antibody | Human | ELISA, WB, IF, IP |
| CSB-PA906175 | ANXA1 (Ab-21) Antibody | Human | ELISA,WB |
| CSB-PA000753 | Phospho-ANXA1 (Y21) Antibody | Human | WB, ELISA |
| CSB-PA000878 | ANXA1 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA009096 | ANXA1 Antibody | Human | WB, ELISA |
| CSB-PA597516 | ANXA1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA061704 | ANXA1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-MA219783 | ANXA1 Monoclonal Antibody | Human | ELISA, IHC |
| CSB-RA001836MA1HU | ANXA1 Recombinant Monoclonal Antibody | Human | ELISA, IHC, FC |
ANXA1 for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA001836HD01MO | Anxa1 Antibody, Biotin conjugated | Mouse | ELISA |
| CSB-PA001836YA01MO | Anxa1 Antibody | Mouse, Human | ELISA, WB, IP |
| CSB-PA001836HC01MO | Anxa1 Antibody, FITC conjugated | Mouse | |
| CSB-PA001836HA01MO | Anxa1 Antibody | Mouse, Human | ELISA, WB |
| CSB-PA001836YD01MO | Anxa1 Antibody, Biotin conjugated | Mouse, Human | ELISA, WB |
ANXA1 Proteins
ANXA1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP001836MO | Recombinant Mouse Annexin A1 (Anxa1) | Yeast |
| CSB-EP001836MO | Recombinant Mouse Annexin A1 (Anxa1) | E.coli |
| CSB-BP001836MO CSB-MP001836MO CSB-EP001836MO-B |
Recombinant Mouse Annexin A1 (Anxa1) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANXA1 Proteins for Cavia cutleri (Guinea pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP001836GU CSB-EP001836GU CSB-BP001836GU CSB-MP001836GU CSB-EP001836GU-B |
Recombinant Guinea pig Annexin A1 (ANXA1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANXA1 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP001836PI CSB-EP001836PI CSB-BP001836PI CSB-MP001836PI CSB-EP001836PI-B |
Recombinant Pig Annexin A1 (ANXA1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANXA1 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP001836BO CSB-EP001836BO CSB-BP001836BO CSB-MP001836BO CSB-EP001836BO-B |
Recombinant Bovine Annexin A1 (ANXA1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANXA1 Proteins for Oryctolagus cuniculus (Rabbit)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP001836RB CSB-EP001836RB CSB-BP001836RB CSB-MP001836RB CSB-EP001836RB-B |
Recombinant Rabbit Annexin A1 (ANXA1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANXA1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-EP001836HU CSB-BP001836HU CSB-MP001836HU CSB-EP001836HU-B |
Recombinant Human Annexin A1 (ANXA1) | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP001836HU1 | Recombinant Human Annexin A1 (ANXA1), partial | E.coli |
| CSB-YP001836HU | Recombinant Human Annexin A1 (ANXA1) | Yeast |
ANXA1 Proteins for Pan troglodytes (Chimpanzee)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP001836EQV CSB-EP001836EQV CSB-BP001836EQV CSB-MP001836EQV CSB-EP001836EQV-B |
Recombinant Pan troglodytes Annexin A1 (ANXA1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANXA1 Proteins for Rodentia sp.
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP001836RFD CSB-EP001836RFD CSB-BP001836RFD CSB-MP001836RFD CSB-EP001836RFD-B |
Recombinant Rodentia sp. Annexin A1 (ANXA1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANXA1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP001836RA CSB-EP001836RA CSB-BP001836RA CSB-MP001836RA CSB-EP001836RA-B |
Recombinant Rat Annexin A1 (Anxa1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANXA1 Proteins for Pongo abelii (Sumatran orangutan)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP001836PYX CSB-EP001836PYX CSB-BP001836PYX CSB-MP001836PYX CSB-EP001836PYX-B |
Recombinant Pongo abelii Annexin A1 (ANXA1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANXA1 Proteins for Equus caballus (Horse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP001836HO CSB-EP001836HO CSB-BP001836HO CSB-MP001836HO CSB-EP001836HO-B |
Recombinant Horse Annexin A1 (ANXA1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANXA1 Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP001836CH CSB-EP001836CH CSB-BP001836CH CSB-MP001836CH CSB-EP001836CH-B |
Recombinant Chicken Annexin A1 (ANXA1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ANXA1 ELISA Kit
ANXA1 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類(lèi)型 | 靈敏度 |
|---|---|---|---|
| CSB-E12155h | Human Annexin Ⅰ(ANX-Ⅰ) ELISA Kit | serum, plasma, tissue homogenates | 0.078 ng/mL |
ANXA1 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類(lèi)型 | 靈敏度 |
|---|---|---|---|
| CSB-EL001836MO | Mouse Annexin A1(ANXA1) ELISA kit | serum, plasma, tissue homogenates | 3.9 ng/ml |
