ADGRE1
ADGRE1，即粘附G蛋白偶聯(lián)受體E1，別名EMR1、TM7LN3、F4/80等。它來(lái)源于人類基因編碼，是G蛋白偶聯(lián)受體2家族中的一員，特別是粘附G蛋白偶聯(lián)受體（ADGR）亞家族的成員。在作用機(jī)制上，ADGRE1參與細(xì)胞黏附過程，并可能涉及免疫系統(tǒng)細(xì)胞間的相互作用。有研究表明，它還可能在調(diào)節(jié)性T細(xì)胞（Treg）的發(fā)育中發(fā)揮作用。ADGRE1與多種生物過程緊密相關(guān)。例如，在非洲家犬中，該基因受到強(qiáng)烈的正選擇，與抵御瘧原蟲侵染的遺傳機(jī)制有關(guān)。通過加強(qiáng)I型干擾素通路相關(guān)基因的表達(dá)量，ADGRE1能夠抵抗瘧原蟲的侵染。ADGRE1在哺乳動(dòng)物單核-巨噬細(xì)胞中也有表達(dá)，顯示了其在免疫系統(tǒng)中的重要作用。
熱銷產(chǎn)品
ADGRE1 Antibody (CSB-PA613493ESR2HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA613493ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA 613493ESR2HU at dilution of 1:100
ADGRE1 Antibodies
ADGRE1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA007651GA01HU | EMR1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA613493ESR2HU | ADGRE1 Antibody | Human | ELISA, IHC |
| CSB-PA008040 | EMR1 Antibody | Human | WB, ELISA |
ADGRE1 Proteins
ADGRE1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP613493HU CSB-EP613493HU CSB-BP613493HU CSB-MP613493HU CSB-EP613493HU-B |
Recombinant Human EGF-like module-containing mucin-like hormone receptor-like 1 (EMR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ADGRE1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP719902RA CSB-EP719902RA CSB-BP719902RA CSB-MP719902RA CSB-EP719902RA-B |
Recombinant Rat EGF-like module-containing mucin-like hormone receptor-like 1 (Emr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ADGRE1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP720253MO CSB-BP720253MO CSB-MP720253MO CSB-EP720253MO-B |
Recombinant Mouse Adhesion G protein-coupled receptor E1 (Adgre1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
