ACTA1
ACTA1，即肌動(dòng)蛋白α1，骨骼肌型，別名ACTA1 Protein，Human，Recombinant（His）等。它來源于人類基因編碼，是肌動(dòng)蛋白家族的一員。ACTA1的主要作用機(jī)制是作為收縮裝置的主要組成部分，在細(xì)胞的運(yùn)動(dòng)、結(jié)構(gòu)和完整性中發(fā)揮著重要作用。ACTA1對(duì)于維持骨骼肌的正常結(jié)構(gòu)和功能至關(guān)重要。該基因的突變可導(dǎo)致多種先天性肌病，如3型向列型肌病、先天性肌?。〗z過細(xì)）、先天性肌?。◣Ш耍┮约跋忍煨约〔。ɡw維型比例失調(diào)）等，這些疾病都會(huì)導(dǎo)致肌纖維缺陷。因此，ACTA1在肌肉疾病的研究和治療中具有重要意義。
熱銷產(chǎn)品
Recombinant Human Actin, alpha skeletal muscle (ACTA1) (CSB-BP001205HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ACTA1 Recombinant Monoclonal Antibody (CSB-RA289956A0HU)
驗(yàn)證數(shù)據(jù)
IHC image of CSB-RA289956A0HU diluted at 1:50 and staining in paraffin-embedded human skeletal muscle tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.72% DAB.
IHC image of CSB-RA289956A0HU diluted at 1:50 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.72% DAB.
Overlay Peak curve showing A549 cells stained with CSB-RA289956A0HU (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1μg/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4℃.Control antibody (green line) was rabbit IgG (1μg/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
ACTA1 Antibodies
ACTA1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA001205GA01HU | ACTA1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA001205NJ01HU | ACTA1 Antibody | Human | ELISA, IHC, IF |
| CSB-PA001205OJ01HU | ACTA1 Antibody | Human | ELISA |
| CSB-PA001205LC01HU | ACTA1 Antibody, FITC conjugated | Human | |
| CSB-PA001205LA01HU | ACTA1 Antibody | Human, Mouse, Rat | ELISA, WB, IHC |
| CSB-PA000383 | ACTA1 Antibody | Human,Mouse,Rat | WB |
| CSB-PA000810 | ACTA1 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA004813 | ACTA1 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA599271 | ACTA1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA084581 | ACTA1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-RA001205A0HU | ACTA1 Recombinant Monoclonal Antibody | Human, Mouse, Rat | ELISA, WB, IHC, IF, FC |
| CSB-RA289956A0HU | ACTA1 Recombinant Monoclonal Antibody | Human | ELISA, IHC, FC |
ACTA1 for H, M, R
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-MA000309 | ACTA1 Monoclonal Antibody | Human,Mouse,Rat | ELISA,WB,IP |
ACTA1 Proteins
ACTA1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001205HU CSB-EP001205HU-B |
Recombinant Human Actin, alpha skeletal muscle (ACTA1) | Yeast In Vivo Biotinylation in E.coli |
| CSB-EP001205HU | Recombinant Human Actin, alpha skeletal muscle (ACTA1) | E.coli |
| CSB-BP001205HU | Recombinant Human Actin, alpha skeletal muscle (ACTA1) | Baculovirus |
| CSB-MP001205HU | Recombinant Human Actin, alpha skeletal muscle(ACTA1) | Mammalian cell |
