CCT4 Antibody

說明書

產品詳情

Uniprot No.：

P50991
基因名：

CCT4
別名：

CCT4 antibody; CCTD antibody; SRB antibody; T-complex protein 1 subunit delta antibody; TCP-1-delta antibody; CCT-delta antibody; Stimulator of TAR RNA-binding antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human CCT4
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.
基因功能參考文獻：
1. Chaperonin CCT is required for the correct folding of eIF3h and eIF3i subunits. PMID: 24320561
2. Both CCT4 and CCT5 homo-oligomers have the property of forming 8-fold double rings absent the other subunits, and these complexes carry out chaperonin reactions without other partner subunits. PMID: 23612981
亞細胞定位：

Cytoplasm. Melanosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body.
蛋白家族：

TCP-1 chaperonin family
數據庫鏈接：

HGNC: 1617

OMIM: 605142

KEGG: hsa:10575

STRING: 9606.ENSP00000377958

UniGene: Hs.421509

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