Recombinant Xenopus laevis Ceramide glucosyltransferase-A (ugcg-a)

in vitro E.coli expression system

中文名稱：

有爪蟾蜍ugcg-a重組蛋白
貨號：

CSB-CF805222XBE
說明書：

MSDS Datasheet
規(guī)格：
來源：

in vitro E.coli expression system
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

基因名：

ugcg-a
Uniprot No.：

Q8AY29
別名：

ugcg-a; ugcg; Ceramide glucosyltransferase-A; XLCGT; UDP-glucose ceramide glucosyltransferase
種屬：

Xenopus laevis (African clawed frog)
蛋白長度：

full length protein
表達區(qū)域：

1-394
氨基酸序列

MAVLDLALQGLAIFGCVLFFVLWFMHFLSIVYTRLHLNKKISDKQPYSKLPGVSLLKPLK GVDPNLINNLETFFELDYPKFEILLCVQDLDDPAVDVCKKLLGKYPSDDAKLFIGGKKVG INPKINNLMPGYEVAKYDLIWICDSGIKVKPDTLTDMANQMTEKVGLVHGLPYVADRQGF AATLEQVYFGTSHPRSYISANVTGFKCVTGMSCLMRKEVLDQAGGLIAFAQYIAEDYFMA KAIADRGWKFSMATQVAMQNSGCYSISQFQSRMIRWAKLRINMLPATIICEPISECFVAS LIIGWAAHHIFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGPLNFSKLDYAVAWFIRESMT IYIFLSALWDPTISWRTGRFRLRCGGTAEEILDV
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標(biāo)簽：

N-terminal 10xHis-tagged
產(chǎn)品提供形式：

Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Catalyzes at the cytosolic surface of the Golgi, the initial step of the glucosylceramide-based glycosphingolipid/GSL synthetic pathway, the transfer of glucose from UDP-glucose to ceramide to produce glucosylceramide/GlcCer. Glucosylceramide is the core component of glycosphingolipids/GSLs, amphipathic molecules consisting of a ceramide lipid moiety embedded in the outer leaflet of the membrane, linked to one of hundreds of different externally oriented oligosaccharide structures. Glycosphingolipids are essential components of membrane microdomains that mediate membrane trafficking and signal transduction. They are implicated in many fundamental cellular processes, including growth, differentiation, migration, morphogenesis, cell-to-cell and cell-to-matrix interactions. Glycosphingolipids are required for convergence extension movements during early development.
基因功能參考文獻：
1. UDP-glucose-ceramide glucosyltransferase (Xlcgt) was expressed both maternally and zigotically persisting at least until stage 35. PMID: 18095347
亞細(xì)胞定位：

Golgi apparatus membrane; Multi-pass membrane protein.
蛋白家族：

Glycosyltransferase 2 family
組織特異性：

At the late gastrula stage, weakly expressed ubiquitously. As neurulation proceeds (stages 15-16), expression moves towards the dorsal structures: involuted paraxial mesoderm and neural folds. In the tailbud embryo (stage 28), expression is restricted to
數(shù)據(jù)庫鏈接：

KEGG: xla:399204

UniGene: Xl.21362