Recombinant Salmonella typhimurium Magnesium transport protein CorA (corA)

in vitro E.coli expression system

中文名稱：

Recombinant Salmonella typhimurium Magnesium transport protein CorA(corA)
貨號：

CSB-CF363297SXB
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

corA
Uniprot No.：

P0A2R8
別名：

corA; STM3952; STMD1.38; Magnesium transport protein CorA
種屬：

Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
蛋白長度：

full length protein
表達區域：

1-316
氨基酸序列

MLSAFQLEKNRLTRLEVEESQSLIDAVWVDLVEPDDDERLRVQSELGQSLATRPELEDIE ASARFFEDEDGLHIHSFFFFEDAEDHAGNSTVAFTIRDGRLFTLRERELPAFRLYRMRAR SQAMVDGNAYELLLDLFETKIEQLADEIENIYSDLEKLSRVIMEGHQGDEYDEALSTLAE LEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQAREILRDIESLLPHNESLFQKVNFL MQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSYGMNFEFMPELKWSFGYPGAIIFMI LAGLAPYLYFKRKNWL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Mediates both influx and efflux of magnesium ions. Can also mediate cobalt and nickel uptake, albeit only at extracellular concentrations that are toxic to the cell. Does not transport iron. Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high.
基因功能參考文獻：
1. Overexpression of the Mg(2+) transporter CorA, which is believed to increase cytoplasmic Mg(2+) levels, decreased mgtA transcription in a manner dependent on a functional mgtA 5' leader. PMID: 19897653
2. does not transport Fe2+ and that the relationship, if any, between iron toxicity and corA is indirect PMID: 15516579
3. affects lactoperoxidase sensitivity but not other oxidative stress PMID: 16269676
4. Data show that a corA mutant is attenuated in mice and defective for invasion of and replication within epithelial cells PMID: 18676664
5. Data show that loss of the CorA protein disrupts a regulatory network(s) with the ultimate phenotype of decreased virulence PMID: 18676666
顯示更多

收起更多
亞細胞定位：

Cell inner membrane; Multi-pass membrane protein.
蛋白家族：

CorA metal ion transporter (MIT) (TC 1.A.35) family
數據庫鏈接：

KEGG: stm:STM3952

STRING: 99287.STM3952