Recombinant Saccharomyces cerevisiae ADIPOR-like receptor IZH2 (IZH2)

in vitro E.coli expression system

中文名稱：

釀酒酵母IZH2重組蛋白
貨號：

CSB-CF622480SVG
說明書：

MSDS Datasheet
規(guī)格：
來源：

in vitro E.coli expression system
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

基因名：

IZH2
Uniprot No.：

Q12442
別名：

IZH2; PHO36; YOL002C; UND327; ADIPOR-like receptor IZH2; Phosphate metabolism protein 36
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

full length protein
表達區(qū)域：

1-317
氨基酸序列

MSTLLERTKSVQELKKRAAGKTSANPAEVAKAKKVLRRLYSWDEIPEWQRDNDFILHGYV KETSSFIETFKSLFYLHNESVNIYSHLIPALGFFTVLLLDKSTIKVFATTTWLDHMVIDL FYSGAFACLILSSSFHCLKSHSLRIATLGNKLDYLGICILIVTSMVSILYYGYFEKFSLF CLFALITVSFGIACSIVSLKDKFRKREWRPYRAGLFVCFGLSSIIPIFSGLYCYSFSEIW TQIQLFWVLLGGVLYIIGAVLYGMRFPEKICPGKFDIWGHSHQLFHFLVVIAALCHLRGL LNSYELVHIKMENGIVS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產(chǎn)品提供形式：

Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Probable receptor, which is involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation.
基因功能參考文獻：
1. Studied yeast Izh2 protein and zinc ion homeostasis and in the regulation of lipid and phosphate metabolism. PMID: 26067383
2. Double disruption of the EOS1 and IZH2 genes yielded a slow-growth phenotype, suggesting that the two proteins are involved in related cellular processes. PMID: 20146743
3. Data show that the protein encoded by ORE20/PHO36 (YOL002c) is an osmotin binding plasma membrane protein that is required for full sensitivity to osmotin. PMID: 15664187
4. Data show that overproduction of Izh2p prevents the iron-dependent induction of the Fet3p component of the high-affinity iron-uptake system and is deleterious for growth in iron-limited medium. PMID: 17553578
5. Izh2p negatively regulates functionally divergent genes through a CCCTC promoter motif. PMID: 18625204
6. Izh2p produces sphingoid bases, bioactive lipids which probably function as the second messenger responsible for the repressive effect of Izh2p on iron-uptake gene FET3. PMID: 19066337
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亞細胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

ADIPOR family
數(shù)據(jù)庫鏈接：

KEGG: sce:YOL002C

STRING: 4932.YOL002C