Recombinant Rat Potassium channel subfamily K member 12 (Kcnk12)

in vitro E.coli expression system

中文名稱：

大鼠Kcnk12重組蛋白
貨號：

CSB-CF872134RA
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

Kcnk12
Uniprot No.：

Q9ERS1
別名：

Kcnk12; Potassium channel subfamily K member 12; Tandem pore domain halothane-inhibited potassium channel 2; THIK-2
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達區域：

1-430
氨基酸序列

MSSRSPRPPPRRCRRRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSAL ESPGEAEARARWGATLRNFSAAHGVAEPELRAFLRHYEAALAAGVRADALRPRWDFPGAF YFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACR ERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVLLACCASAMYTSVEG WDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISI LIKQVLNWMLRKLSCRCCTRCCPAPGAPLSRRNAITPGSRLRRRLAALGTDPAARDSDAE GRRLSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMN NRLAETSASR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel.
基因功能參考文獻：
1. the characteristics of THIK-2 channels can be analysed in heterologous expression systems by using trafficking and/or gating mutants PMID: 24297522
2. THIK-1 and THIK-2 are abundantly expressed in the proximal and distal nephron of the mammalian kidney. PMID: 18209473
亞細胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

Two pore domain potassium channel (TC 1.A.1.8) family
組織特異性：

Highly expressed in most brain regions. Also expressed in other tissues such as lung, kidney, liver, stomach and spleen.
數據庫鏈接：

KEGG: rno:64119

STRING: 10116.ENSRNOP00000021570

UniGene: Rn.64577