Recombinant Mouse Vezatin (Vezt)

in vitro E.coli expression system

中文名稱(chēng)：

小鼠Vezt重組蛋白
貨號(hào)：

CSB-CF671380MO
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

in vitro E.coli expression system
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

基因名：

Vezt
Uniprot No.：

Q3ZK22
別名：

Vezt; Vezatin
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

full length protein
表達(dá)區(qū)域：

1-780
氨基酸序列

MTPEFDEEVVFENSPLYQYLQDLGHTDFEICSSSSPKPEKCLTTEGPQPPPTRVLQRQGI LLKLTETIKSWTFSSQHSKKDDLLHKLDTGFRLDSLHTILQQEVLLQEDVELLELLDASI LSAGQPQQESGHLPTLCSLATPNTWDVSLLFAFISLLIMFPTCWIVSSWLVWGIILFLYL IIRVLKLWRTAKLQMTLKKYRVRLEDMAANSRAFTNLVRKSLRLIQETEVISRGFTLVSA ACSFNKAAQHPGQHLIGLRKAVYRTVRANFQAARLATLYMLKNYPLNSESDNVTNYICVV PFKELGLGLSEDQISEEEARNLTDGFSLPALKVLFQLWVAQSSEFFRRLALLLSTANSPS GPLLTAALLPHHILCDVTQGLPHAHSACLDELKRSYEFFRYFETQHQSVPQRLSKTPQKS RELSNVHTAVRSLQLHLKALLNEVIILEDELEKLVCTKETQELLSEAYPILEQKLKLIEP HVQASNSCWEEAISQVDKLLRRNTDKKGKPGVACENPHCTAEPLVRPALHIEDRDPIPEE QELEAYVDDIDIESEFRKDDFYHLSQEDRERQKREQEESRRVLQELKSVLGFKASEAERQ KWKQLLFSDHAVLTSLSPVDPVESVSNSEPPMNSDTEKVNSNATEEETSKPCAGDKEDSR TEYVCDSPTEGPSKDTSADTGLLLPGAEETMCHQHESEAKSPQAAAAGATAPPTPRDTLQ LSIKQRLARLQLPPEFTFSAGLAAEVAARSLSFTTMQEQTFGDEEEEQLVEGGENEVEEK
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標(biāo)簽：

N-terminal 10xHis-tagged
產(chǎn)品提供形式：

Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Plays a pivotal role in the establishment of adherens junctions and their maintenance in adult life. Required for morphogenesis of the preimplantation embryo, and for the implantation process.
基因功能參考文獻(xiàn)：
1. These results suggest a role of Vezatin in dendritic spine morphogenesis and functional synaptic maturation. PMID: 22745500
2. present study suggests that vezatin may regulate dendritic formation as a downstream effector of ARF6. PMID: 20188128
3. vezatin associates with actin filaments at cell-cell junctions. PMID: 20049712
4. Required for morphogenesis of the preimplantation mouse embryo. PMID: 16199027
5. These in vitro observations reinforce the idea that homozygous vezatin-null mutants die at the time of implantation because of a defect in intercellular adhesion. PMID: 17452094
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亞細(xì)胞定位：

Cell membrane; Multi-pass membrane protein. Cell projection, stereocilium membrane. Cell junction, adherens junction. Nucleus. Cytoplasmic vesicle, secretory vesicle, acrosome.
蛋白家族：

Vezatin family
組織特異性：

Expressed in developing cochlear hair cells. Isoform 1, isoform 2 and isoform 3 are expressed in testis. In the seminiferous epithelium, present exclusively in the acrosome of spermatids (at protein level).
數(shù)據(jù)庫(kù)鏈接：

KEGG: mmu:215008

STRING: 10090.ENSMUSP00000037955

UniGene: Mm.124177