Recombinant Dog Solute carrier family 2, facilitated glucose transporter member 4 (SLC2A4)

in vitro E.coli expression system

中文名稱：

熟悉的犬SLC2A4重組蛋白
貨號：

CSB-CF895472DO
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

SLC2A4
Uniprot No.：

Q9XST2
別名：

SLC2A4; GLUT4; B146; Solute carrier family 2, facilitated glucose transporter member 4; Glucose transporter type 4, insulin-responsive; GLUT-4; Fragment
種屬：

Canis familiaris (Dog) (Canis lupus familiaris)
蛋白長度：

full length protein
表達區域：

1-162
氨基酸序列

TSIFETAGVGQPAYATIGAGVVNTVFTLVSVFLVERAGRRTLHLLGLAGMCGCAILMTIA LLLLERLPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFCNWTS NFIIGMGFQYIAXAMGPYVFLLFAVLLLAFFIFTFLKVPETR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell.
基因功能參考文獻：
1. Results indicate that the state of conditioning had a significant effect on the glucose transporter-4 protein (GLUT4) expression at the surface of mononuclear cells. PMID: 25236492
2. Damage of cardiac function during cardiopulomnary bypass are mostly associated with lower expression of Glut-4 mRNA. PMID: 23111893
3. Chronic heart failure selectively induces regional heterogeneity of insulin-responsive glucose transporters, GLUT4/12. PMID: 21849635
4. Suppressed translocation of GLUT-4 was also evident in dogs receiving 30-min ischemia PMID: 18535164
亞細胞定位：

Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region.
蛋白家族：

Major facilitator superfamily, Sugar transporter (TC 2.A.1.1) family, Glucose transporter subfamily
數據庫鏈接：

KEGG: cfa:403673

STRING: 9615.ENSCAFP00000023753

UniGene: Cfa.3539