Recombinant Bovine N-arachidonyl glycine receptor (GPR18)

in vitro E.coli expression system

中文名稱：

牛GPR18重組蛋白
貨號：

CSB-CF660985BO
說明書：

MSDS Datasheet
規(guī)格：
來源：

in vitro E.coli expression system
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關產(chǎn)品
靶點詳情

產(chǎn)品詳情

基因名：

GPR18
Uniprot No.：

Q3T0E9
別名：

GPR18; N-arachidonyl glycine receptor; NAGly receptor; G-protein coupled receptor 18
種屬：

Bos taurus (Bovine)
蛋白長度：

full length protein
表達區(qū)域：

1-332
氨基酸序列

MTTPHSQAQPGLPIDPHPDEYKVAALVFYSCIFIIGLFVNVTALWVFSCTTKKRTTVTVY MMNVALLDLVFIMSLPFRMLYYAKGEWPFGEYFCRILGALTVFYPSIALWLLAFISADRY MAIVQPKYAKELKNTCKAVMACVGVWIMTLTTTIPLLLLYEDPDTASSTPPTCLKISDII YLKAINALNFTRLIFFFLIPLFIMIGCYLVIIHSLLHGKTSKLKPKVKEKSIRIIITLMV QVLVCFMPFHICFAFLMLGGDENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVIS VMLYRNYLRSVRRKSFRSGSLRSLSNINSEML
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產(chǎn)品提供形式：

Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Receptor for endocannabinoid N-arachidonyl glycine (NAGly). However, conflicting results about the role of NAGly as an agonist are reported. Can also be activated by plant-derived and synthetic cannabinoid agonists. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system. Is required for normal homeostasis of CD8+ subsets of intraepithelial lymphocytes (IELs) (CD8alphaalpha and CD8alphabeta IELs) in small intstine by supporting preferential migration of CD8 alphaalpha T-cells to intraepithelial compartment over lamina propria compartment, and by mediating their reconstitution into small intestine after bone marrow transplant. Plays a role in hypotensive responses, mediating reduction in intraocular and blood pressure. Mediates NAGly-induced process of reorganization of actin filaments and induction of acrosomal exocytosis.
亞細胞定位：

Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane.
蛋白家族：

G-protein coupled receptor 1 family
數(shù)據(jù)庫鏈接：

KEGG: bta:540038

STRING: 9913.ENSBTAP00000007469

UniGene: Bt.92549