HEK293/Human CLDN9-eGFP Stable Cell Line

貨號：

CSB-SC005511HU
規格：

1 vial contains approximately 5x10⁶ cells in 1 ml
價格：

￥30000
活性：
Untransfected HEK-293 cells (green line) and transfected Human CLDN9 HEK-293 stable cells (red line) were stained with anti-CLDN6/9 antibody(CSB-RA005508MA1HU) (2μg/1*10⁶cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.

Untransfected HEK-293 cells (green line) and transfected Human CLDN9 HEK-293 stable cells (red line) were stained with anti-CLDN6/9 antibody(CSB-RA005508MA3HU) (2μg/1*10⁶cells), washed and then followed by APC-conjugated anti-Mouse IgG Fc antibody and analyzed with flow cytometry.
其他：

產品詳情

Uniprot No.：

O95484
生長類型：

Adherent
抗性：

Puromycin
培養基：

DMEM + 10% FBS + 0.75 μg/mL Puromycin
別名：

CLDN9
蛋白標簽：

C-terminal eGFP-tagged
保存緩沖液：

35% FBS + 55% DMEM + 10% DMSO
應用范圍：

Binding assay by FACS and cell based ELISA.
儲存條件：

Frozen in liquid nitrogen or -80°C
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

功能：

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.; (Microbial infection) Acts as a receptor for hepatitis C virus (HCV) entry into hepatic cells.
基因功能參考文獻：
1. CLDN9 may be an important biomarker for invasive pituitary oncocytomas. PMID: 25281028
2. Claudins 6, 7, and 9 expressions are closely related to gastric carcinogenesis. PMID: 19960275
3. Mouse studies suggest that claudin-9 deficiency may cause hearing loss not only in mice but also in humans. PMID: 19696885
4. Residues N38 and V45 in the first extracellular loop (EL1) of CLDN9 are necessary for HCV entry. PMID: 17804490
5. CLDN9, clustered with CLDN6 at human chromosome 16p13.3, is a four-transmembrane protein with WWCC motif, defined by W-X(17-22)-W-X(2)-C-X(8-10)-C. PMID: 12736707
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亞細胞定位：

Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
蛋白家族：

Claudin family
組織特異性：

Expressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines.
數據庫鏈接：

HGNC: 2051

OMIM: 615799

KEGG: hsa:9080

STRING: 9606.ENSP00000398017

UniGene: Hs.296949

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