Recombinant Xenopus tropicalis DNA damage-binding protein 2 (ddb2), partial

中文名稱：

Recombinant Xenopus tropicalis DNA damage-binding protein 2(ddb2) ,partial
貨號：

CSB-YP714898XBF
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Xenopus tropicalis DNA damage-binding protein 2(ddb2) ,partial
貨號：

CSB-EP714898XBF
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Xenopus tropicalis DNA damage-binding protein 2(ddb2) ,partial
貨號：

CSB-EP714898XBF-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Xenopus tropicalis DNA damage-binding protein 2(ddb2) ,partial
貨號：

CSB-BP714898XBF
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Xenopus tropicalis DNA damage-binding protein 2(ddb2) ,partial
貨號：

CSB-MP714898XBF
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ddb2
Uniprot No.：

Q66JG1
別名：

ddb2DNA damage-binding protein 2; Damage-specific DNA-binding protein 2
種屬：

Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
蛋白長度：

Partial
表達區域：

1-501
氨基酸序列

MPPKRATRGR RNVELSSEEE EEQEEVSPGK RKRDIEKNGE ARLKKPSKKR SGQQCASDVP CSSKESDCGT NLTNKGDKQR SIVHYLYRST LGGNVRAKYL QTPFLRSLAS YILYRTNSPF DRRVTTLEWH PTHPNTVAVG SKGGDIILWD YEELNNTLIP GIGAGGCITG MKFDPFNPNQ LYTSSVAGST VLQDFSGRNI QTFTNTEDWA MWYCSLDVSA ERQCVVTGDN VGNVVLLETC GKEIWKLRLH KKKVTHVEFN PRCDWLLASA SVDQTVKLWD LRNIKDKSSY LYTLPHARGV NSAYFSPWDG AKLLTTDQHS EIRVYSACDW AKPQHIIPHP HRQFQHLTAI KATWHPRYDL IVVGRYPDPL FPGYMSDELR TVDVFDGQKG NIVCQLYDPY ASGIVSLNKF NPMGDLLASG MGFNILIWSR EILLMMKQEE MMKALREKGV SVGRKELPNS RLPHSSAPRE KPGNKGSTTE SSKTRTVRES SKRGKHKDPG K
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Protein, which is both involved in DNA repair and protein ubiquitination, as part of the UV-DDB complex and DCX (DDB1-CUL4-X-box) complexes, respectively. Core component of the UV-DDB complex (UV-damaged DNA-binding protein complex), a complex that recognizes UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD), 6-4 photoproducts (6-4 PP), apurinic sites and short mismatches. Also functions as the substrate recognition module for the DCX (DDB2-CUL4-X-box) E3 ubiquitin-protein ligase complex DDB2-CUL4-ROC1 (also known as CUL4-DDB-ROC1 and CUL4-DDB-RBX1). The DDB2-CUL4-ROC1 complex may ubiquitinate histone H2A, histone H3 and histone H4 at sites of UV-induced DNA damage. The ubiquitination of histones may facilitate their removal from the nucleosome and promote subsequent DNA repair.
亞細胞定位：

Nucleus.
蛋白家族：

WD repeat DDB2/WDR76 family
數據庫鏈接：

KEGG: xtr:493565

STRING: 8364.ENSXETP00000008619

UniGene: Str.26784