Recombinant Xenopus laevis Serine/threonine-protein kinase Sgk1-A (sgk1-a)

中文名稱：

有爪蟾蜍sgk1-a重組蛋白
貨號：

CSB-YP743445XBE
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

有爪蟾蜍sgk1-a重組蛋白
貨號：

CSB-EP743445XBE
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

有爪蟾蜍sgk1-a重組蛋白
貨號：

CSB-EP743445XBE-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

有爪蟾蜍sgk1-a重組蛋白
貨號：

CSB-BP743445XBE
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

有爪蟾蜍sgk1-a重組蛋白
貨號：

CSB-MP743445XBE
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

sgk1-a
Uniprot No.：

Q6GPN6
別名：

sgk1-a; sgk-a; Serine/threonine-protein kinase Sgk1-A; EC 2.7.11.1; Serum/glucocorticoid-regulated kinase 1-A
種屬：

Xenopus laevis (African clawed frog)
蛋白長度：

full length protein
表達區域：

1-434
氨基酸序列

MTVKTETAAG ASTLTYSKMR GMVALLIAFM KQRRMGLNDF IQKIATNSSY ACKPSEVQSI LNISPPQEPE LLNENSSPPP SPSQQINLGP SSNPHAKPSD FQFLKIIGKG SFGKVLLARH QADEKFYAVK VLQKKAILKK KEEKHIMSER NVLLKNVKHP FLVGLHFSFQ TTSRLYFILD YINGGELFYH LQRERCFLEP RARFYAAEIA SALGYLHSLN IVYRDLKPEN ILLDSQGHIV LTDFGLCKEN IEPNGTTSTF CGTPEYLAPE VLHKQPYDRT VDWWCLGAVL YEMLYGLPPF YSRNTAEMYD NILNKPLQLK PNITNSARNL LEGLLQKDRT KRIGAKNDFM EIKNHIFFSP INWDDLINKK ITPPFNPNVS GPSDLQHFDP EFTEEPVPNS IGQSPDSILI TASIKEAAEA FMGFSYAPPM ESYL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Protein kinase that may play an important role in cellular stress response. Plays an important role in activating certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion.
基因功能參考文獻：
1. The kinase SGK1 in the endoderm and mesoderm promotes ectodermal survival by down-regulating components of the death-inducing signaling complex. PMID: 21245468
2. ENaC-beta regulation that occurs through IKKbeta-dependent Nedd4-2 phosphorylation at a recognized SGK1 and protein kinase A target site. PMID: 18981174
3. SGK1 might participate in the regulation of insulin secretion in part by controlling Kv1.5 surface abundance. PMID: 19088441
亞細胞定位：

Cytoplasm. Nucleus. Endoplasmic reticulum.
蛋白家族：

Protein kinase superfamily, AGC Ser/Thr protein kinase family
數據庫鏈接：

KEGG: xla:399130

UniGene: Xl.7842