Recombinant Xenopus laevis Insulin-like growth factor 2 mRNA-binding protein 3-A (igf2bp3-a), partial

中文名稱：

有爪蟾蜍igf2bp3-a重組蛋白
貨號：

CSB-YP526683XBE
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

有爪蟾蜍igf2bp3-a重組蛋白
貨號：

CSB-EP526683XBE
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

有爪蟾蜍igf2bp3-a重組蛋白
貨號：

CSB-EP526683XBE-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

有爪蟾蜍igf2bp3-a重組蛋白
貨號：

CSB-BP526683XBE
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

有爪蟾蜍igf2bp3-a重組蛋白
貨號：

CSB-MP526683XBE
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

igf2bp3-a
Uniprot No.：

O73932
別名：

igf2bp3-a; vera-a; vickz3-aInsulin-like growth factor 2 mRNA-binding protein 3-A; IGF2 mRNA-binding protein 3-A; IMP-3-A; 69 kDa RNA-binding protein A; IGF-II mRNA-binding protein 3-A; KH domain-containing transcription factor B3-A; RNA-binding protein Vera-A; Trans-acting factor B3-A; VICKZ family member 3-A; VLE-binding protein A; Vg1 RNA-binding protein A; Vg1 RBP-A; Vg1 localization element binding protein A; VgLE-binding and ER association protein A
種屬：

Xenopus laevis (African clawed frog)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

RNA-binding protein that act as a regulator of mRNA transport and localization. Mediates the specific association of Vg1 RNA to microtubules. Binds specifically to the vegetal localization elements (VLE or VgLE) in the 3'-UTR of Vg1 and VegT mRNAs. Binds to the Vg1 and VegT mRNAs in both the nucleus and the cytoplasm. Binds to the RNA sequence motif 5'-UUCAC-3'. May regulate mRNA translation. Acts as a transcription regulator. Binds to the 5'-[TA]GGTTACT-3' motif within element 3 of the TFIIIA gene promoter. Binds DNA.
基因功能參考文獻：
1. Findings show that Vg1RBP is required for terminal arborization but not long-range axon navigation and suggest that Vg1RBP-regulated mRNA translation promotes synaptic complexity PMID: 23853158
2. the motif binding protein Vera has a role during Vg1-dependent mRNA localization PMID: 16373488
3. the motif binding proteins Vera and hnRNP I have differing roles during Vg1-dependent mRNA localization PMID: 16373488
4. The ability of VICKZ/Vg1 proteins to mediate cell migration, in vitro and in vivo, requires their RNA binding activity. PMID: 17652133
5. Vg1RBP phosphorylation by Erk2 MAP kinase correlates with the cortical release of Vg1 mRNA during meiotic maturation of Xenopus oocytes PMID: 19376927
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亞細胞定位：

Nucleus. Cytoplasm. Endoplasmic reticulum. Note=Accumulates along the vegetal cortex in oocytes as oogenesis progresses ('late pathway' for RNA localization). Colocalizes with Vg1 RNA along the vegetal cortex.
蛋白家族：

RRM IMP/VICKZ family
數據庫鏈接：

KEGG: xla:394293

UniGene: Xl.319