Recombinant Staphylococcus aureus Iron-regulated surface determinant protein A (isdA)

^{In
Stock}

文獻引用 (3)

中文名稱：

金黃色釀膿葡萄球菌isdA重組蛋白
貨號：

CSB-EP763937SKW
說明書：

MSDS Datasheet
規格：

￥2328
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP763937SKW could indicate that this peptide derived from E.coli-expressed Staphylococcus aureus (strain MSSA476) isdA.

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP763937SKW could indicate that this peptide derived from E.coli-expressed Staphylococcus aureus (strain MSSA476) isdA.
其他：

產品詳情
產品評價
引用文獻
相關產品
靶點詳情

產品詳情

純度：

Greater than 85% as determined by SDS-PAGE.
基因名：

isdA
Uniprot No.：

Q6GA85
別名：

isdA; frpA; stbA; SAS1064Iron-regulated surface determinant protein A; Fur-regulated protein A; Staphylococcal transferrin-binding protein A
種屬：

Staphylococcus aureus (strain MSSA476)
蛋白長度：

Full Length of Mature Protein
來源：

E.coli
分子量：

35.1 kDa
表達區域：

47-316aa
氨基酸序列

ATEATNATNNQSTQVSQATSQPINFQVQKDGSSEKSHMDDYMQHPGKVIKQNNKYYFQTVLNNASFWKEYKFYNANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIVVPQINYNHRYTTHLEFEKAIPTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVSTDTTKDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKHNETPKQASKAKELPKT
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged and C-terminal Myc-tagged
產品提供形式：

Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Tris-based buffer,50% glycerol
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

3-7 business days
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

引用文獻

Enhanced optical aptasensing platform utilizing mesoporous silica nanoparticles for the detection of iron-regulated surface determinant protein A N Ullah, TA Bruce-Tagoe, GA Asamoah,Microchemical Journal,2025
Surface plasmon resonance aptasensing and computational analysis of Staphylococcus aureus IsdA surface protein TA Bruce‐Tagoe,Biotechnology progress,/
Evaluation of three Staphylococcus aureus proteins involved in the adhesion process as antigens for the detection of bovine intramammary infections G Torres,Journal of Medical Microbiology,2023

產品評價

靶點詳情

功能：

Cell wall-anchored surface receptor that participates in the extraction of heme from oxidized methemoglobin/metHb to enable growth on hemoglobin as a sole iron source. Receives heme from IsdB and transfers it to IsdC. Plays also a role in the inhibition of host immune response. Protects S.aureus against the bactericidal protease activity of apolactoferrin. Enhances bacterial cellular hydrophobicity, which renders S.aureus resistant to bactericidal human skin fatty acids as well as to beta-defensins and cathelicidin. Also binds fibronectin and chains B-beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization.
亞細胞定位：

Secreted, cell wall; Peptidoglycan-anchor.
數據庫鏈接：

KEGG: sas:SAS1064