Recombinant Splicing factor U2AF 65 kDa subunit (uaf-1)

中文名稱：

秀麗隱桿線蟲uaf-1重組蛋白
貨號：

CSB-YP025408CXY
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

秀麗隱桿線蟲uaf-1重組蛋白
貨號：

CSB-EP025408CXY
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

秀麗隱桿線蟲uaf-1重組蛋白
貨號：

CSB-EP025408CXY-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

秀麗隱桿線蟲uaf-1重組蛋白
貨號：

CSB-BP025408CXY
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

秀麗隱桿線蟲uaf-1重組蛋白
貨號：

CSB-MP025408CXY
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

uaf-1
Uniprot No.：

P90978
別名：

uaf-1; Y92C3B.2; Splicing factor U2AF 65 kDa subunit; U2 auxiliary factor 65 kDa subunit; U2AF65; U2 snRNP auxiliary factor large subunit
種屬：

Caenorhabditis elegans
蛋白長度：

full length protein
表達(dá)區(qū)域：

1-496
氨基酸序列

MSDHQDGMKL EDIERQFLDV AQREGGLEAI QPTTGPLENE ENLKSSTGGG GGEDDNDRKK RKRSRSRDRD TRRRSRSRDR GERRGGGGGG DRDRSRSRER RRGGGGRDEP RRRGGDDEAR SRREPEPQKP REPKKYRFWD VPPTGFETTT PMEYKNMQAA GQVPRGSVQS AVPVVGPSVT CQSRRLYVGN IPFGCNEEAM LDFFNQQMHL CGLAQAPGNP ILLCQINLDK NFAFIEFRSI DETTAGMAFD GINFMGQQLK VRRPRDYQPS QNTFDMNSRM PVSTIVVDSA NKIFIGGLPN YLTEDQVKEL LCSFGPLKAF SLNVDSQGNS KGYAFAEYLD PTLTDQAIAG LNGMQLGDKQ LVVQLACANQ QRHNTNLPNS ASAIAGIDLS QGAGRATEIL CLMNMVTEDE LKADDEYEEI LEDVRDECSK YGIVRSLEIP RPYEDHPVPG VGKVFVEFAS TSDCQRAQAA LTGRKFANRT VVTSYYDVDK YHNRQF
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Necessary for the splicing of pre-mRNA. Binds to the polypyrimidine tract of introns early during spliceosome assembly.
基因功能參考文獻(xiàn)：
1. WDR-20 and WDR-48 form a complex with USP-46 and stimulate the DUB to deubiquitinate and stabilize GLR-1 in vivo. PMID: 24356955
2. The interaction of TEG-1 CD2BP2 with UAF-1 U2AF65, combined with its previously described function in U4/U6.U5 tri-snRNP, suggests that TEG-1 CD2BP2 functions in two distinct locations in the splicing cascade. PMID: 22275078
3. Mutations in the splicing factors U2AF large subunit altered the splicing of tos-1. 3' splice sites. PMID: 22033331
4. observations provide in vivo evidence that UAF-1 can act in regulating 3' splice-site choice and establish a system that can be used to investigate the in vivo regulation of RNA splicing in C. elegans. PMID: 19893607
亞細(xì)胞定位：

Nucleus.
數(shù)據(jù)庫鏈接：

KEGG: cel:CELE_Y92C3B.2

STRING: 6239.Y92C3B.2a

UniGene: Cel.18058