Recombinant Sicarius terrosus Sphingomyelin phosphodiesterase D StSicTox-betaIC1

中文名稱：

Recombinant Sicarius terrosus Sphingomyelin phosphodiesterase D StSicTox-betaIC1
貨號：

CSB-YP497554SZJ
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Sicarius terrosus Sphingomyelin phosphodiesterase D StSicTox-betaIC1
貨號：

CSB-EP497554SZJ
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Sicarius terrosus Sphingomyelin phosphodiesterase D StSicTox-betaIC1
貨號：

CSB-EP497554SZJ-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Sicarius terrosus Sphingomyelin phosphodiesterase D StSicTox-betaIC1
貨號：

CSB-BP497554SZJ
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Sicarius terrosus Sphingomyelin phosphodiesterase D StSicTox-betaIC1
貨號：

CSB-MP497554SZJ
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

N/A
Uniprot No.：

C0JB39
別名：

Dermonecrotic toxin StSicTox-betaIC1; EC 4.6.1.-; Phospholipase D; PLD; Sphingomyelin phosphodiesterase D; SMD; SMase D; Sphingomyelinase D; Fragment
種屬：

Sicarius terrosus (Cave spider)
蛋白長度：

full length protein
表達區域：

1-272
氨基酸序列

WIMGHMVNDL DLVDEYLDDG ANSLELDVEF SKSGTALRTY HGVPCDCFRS CTRSEKFSKY LDYIRQLTTP GNSKFRSRLI LLVLDLKLNP LSSSAAYNAG ADVARNLLDN YWQRGESKAR AYIVLSLETI AGAEFITGFK DIMKKEGFDE KYYDKIGWDF SGNEDLGKIR DVLESHGIRE HIWQGDGITN CLPRDDNRLK QAISRRYSPT YVYADKVYTW SIDKESSIEN ALRLGVDGVM TNYPARVISV LGEREFSGKL RLATYDDNPW EK
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate. This toxin acts on lysophosphatidylethanolamine (LPE) and ceramide phosphoethanolamine (CPE) with high activity. This toxin acts on sphingomyelin (SM) with very low activity and is not active on lysophosphatidylserine (LPS), lysophosphatidylcholine (LPC) and lysophosphatidylglycerol (LPG). It acts by transphosphatidylation, releasing exclusively cyclic phosphate as second products. It is not surprising that spider toxins have affinity for ethanolamine-containing sphingolipids since they are common in insect prey. Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation.
亞細胞定位：

Secreted.
蛋白家族：

Arthropod phospholipase D family, Class II subfamily
組織特異性：

Expressed by the venom gland.