Recombinant Sheep Shadow of prion protein (SPRN)

中文名稱：

綿羊SPRN重組蛋白
貨號：

CSB-YP022609SH
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

綿羊SPRN重組蛋白
貨號：

CSB-EP022609SH
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

綿羊SPRN重組蛋白
貨號：

CSB-EP022609SH-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

綿羊SPRN重組蛋白
貨號：

CSB-BP022609SH
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

綿羊SPRN重組蛋白
貨號：

CSB-MP022609SH
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

SPRN
Uniprot No.：

A6XN32
別名：

SPRN; Shadow of prion protein; Protein shadoo
種屬：

Ovis aries (Sheep)
蛋白長度：

Full Length of Mature Protein
表達區域：

25-119
氨基酸序列

KGGRGG ARGSARGGRG AARVRVRPAP RYAGSSVRAA AGAAAGAAAA AGVAAGLAAG SSWRRAAGPA ELGLEDAEDG APGSNGTGRG VYSYWAWTS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 668
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP.
基因功能參考文獻：
1. A probable role for the heterozygous genotype of SPRN 6-bp indel polymorphism in the susceptibility of Polish sheep to atypical scrapie. PMID: 21674189
2. Study analysed mutations in the ovine SPRN gene, their association with scrapie susceptibility and promoter activity; 26 mutations were found: 7 in the promoter region, 4 in intron 1, 7 in the coding sequence and 8 in the 3' untranslated region. PMID: 19917049
3. The relative mRNA expression levels of SPRN and PRNP in sheep cerebrum and cerebellum and the mutual relationship between these expression levels were investigated. PMID: 19059475
亞細胞定位：

Cell membrane; Lipid-anchor, GPI-anchor.
蛋白家族：

SPRN family
組織特異性：

Mainly expressed in brain.
數據庫鏈接：

KEGG: oas:100302330

UniGene: Oar.19976