Recombinant Schizosaccharomyces pombe DNA damage response protein wss1 (wss1)

中文名稱：

龐貝裂殖酵母SPAC521.02重組蛋白
貨號：

CSB-YP873779SXV
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

龐貝裂殖酵母SPAC521.02重組蛋白
貨號：

CSB-EP873779SXV
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

龐貝裂殖酵母SPAC521.02重組蛋白
貨號：

CSB-EP873779SXV-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

龐貝裂殖酵母SPAC521.02重組蛋白
貨號：

CSB-BP873779SXV
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

龐貝裂殖酵母SPAC521.02重組蛋白
貨號：

CSB-MP873779SXV
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

SPAC521.02
Uniprot No.：

Q9P7B5
別名：

SPAC521.02DNA-dependent metalloprotease WSS1 homolog; EC 3.4.24.-; DNA damage response protein WSS1 homolog
種屬：

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
蛋白長度：

full length protein
表達區域：

1-283
氨基酸序列

MIAILYLYYI LTTSILLSVS FMLRINDDDH PNEKIGFISA IKGDFHDLSS DYLKRIAAMA FPIMKEHGFG VTSLDEVAYN AKFWGRNWNK GECIELVLRD ASNRWLPFEF VMDVFLHELC HIWQGPHDRR FFSHLSTLRA ALIALYAKGY KGPGKYMTWD SFVLANVVGN YNTVVFNGIT LERSTMHGVE TCGGSLQRKK KIRRKPTPSS TKKRKLTRTG QKLGTDMNIR LELLKSPAKP QAQSMRGREA RIAAALLRVD NSNEYKPKDH NSSTTLENYF VVE
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Metalloendopeptidase that acts selectively on DNA-binding proteins. DNA is needed to bring the protease and substrates together to enable proteolysis. Involved in the repair of toxic DNA-protein cross-links (DPCs) such as covalently trapped topoisomerase 1 (top1) adducts on DNA lesions or DPCs induced by reactive compounds such as formaldehyde. Involved in DNA damage response and processing of stalled or collapsed replication forks by removing the covalently trapped top1 from chromatin. DPC proteolysis enables the repair of the lesions via downstream DNA repair pathways. May be recruited to DPCs via the SUMOylation of substrate proteins at damaged DNA sites.
亞細胞定位：

Nucleus.
蛋白家族：

Peptidase M3 family, WSS1-like metalloprotease (WLM) subfamily
數據庫鏈接：

KEGG: spo:SPAC521.02

STRING: 4896.SPAC521.02.1