Recombinant Salmonella typhimurium E3 ubiquitin-protein ligase SopA (sopA), partial

中文名稱：

鼠傷寒沙門菌sopA重組蛋白
貨號：

CSB-YP845778SXB
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

鼠傷寒沙門菌sopA重組蛋白
貨號：

CSB-EP845778SXB
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

鼠傷寒沙門菌sopA重組蛋白
貨號：

CSB-EP845778SXB-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

鼠傷寒沙門菌sopA重組蛋白
貨號：

CSB-BP845778SXB
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

鼠傷寒沙門菌sopA重組蛋白
貨號：

CSB-MP845778SXB
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

sopA
Uniprot No.：

Q8ZNR3
別名：

sopA; STM2066; E3 ubiquitin-protein ligase SopA; EC 2.3.2.26; HECT-type E3 ubiquitin transferase SopA; Salmonella outer protein A; Secreted effector protein SopA
種屬：

Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

功能：

Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway. Required for inducing polymorphonuclear leukocytes migration across the intestinal epithelium. Preferentially uses host UBE2D1 (UBCH5A), UBE2D2 (UBCH5B) and UBE2L3 (UBCH7) as E2 ubiquitin-conjugating enzymes.
基因功能參考文獻(xiàn)：
1. Efficient bacterial escape into the cytosol of epithelial cells requires HsRMA1-mediated SopA ubiquitination and contributes to Salmonella-induced enteropathogenicity PMID: 16176924
2. SopA preferentially uses the host proteins, which are involved in inflammation.SopA ubiquitinate bacterial/host proteins involved in Salmonella-induced intestinal inflammation PMID: 17076670
3. These results suggest that Dam methylation modulates the expression and secretion of SopA in Salmonella Typhimurium. PMID: 19191875
亞細(xì)胞定位：

Secreted. Host cell.
蛋白家族：

SopA E3 ligase family
數(shù)據(jù)庫鏈接：

KEGG: stm:STM2066

STRING: 99287.STM2066