Recombinant Salmonella typhimurium Cyclic di-GMP regulator CdgR (cdgR)

中文名稱：

鼠傷寒沙門菌ydiV重組蛋白
貨號：

CSB-YP841832SXB
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

鼠傷寒沙門菌ydiV重組蛋白
貨號：

CSB-EP841832SXB
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

鼠傷寒沙門菌ydiV重組蛋白
貨號：

CSB-EP841832SXB-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

鼠傷寒沙門菌ydiV重組蛋白
貨號：

CSB-BP841832SXB
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

鼠傷寒沙門菌ydiV重組蛋白
貨號：

CSB-MP841832SXB
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ydiV
Uniprot No.：

Q8ZPS6
別名：

ydiV; cdgR; STM1344; Anti-FlhC(2)FlhD(4) factor YdiV; EAL-like protein YdiV; c-di-GMP regulator CdgR
種屬：

Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
蛋白長度：

full length protein
表達區域：

1-237
氨基酸序列

MIASLDELYH SELFFLPVMD ENARLVGLEI IATFAAEDGA VRMPTELVAP RLSVEEQYCL FVEKLALLET CQHFFIQHKL IAWLNLPPAI SDLLLLDSEL FSRAARFPFL ELAINENYPG LNQGKNNETL ANLAMHFPLM LANFGAGEAS TKAIFDGLFK RVMLDKNFIQ QRAEMISFEP FMHAIVAQIS SSCESLMIAG IDTEAMFARA APLGFSAFQG GLWPPVPVSQ LIKLVQR
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Acts as an anti-FlhC(2)FlhD(4) factor by binding to FlhD, decreasing its ability to bind DNA, and thus negatively regulates expression of flagellar class II operons, decreasing motility in nutrient-poor medium. Required for resistance to host phagocyte oxidase. Suppresses killing of macrophages, while promoting resistance to hydrogen peroxide. Data regarding c-di-GMP is controversial; suppresses bacterial c-di-GMP levels but neither synthesizes nor degrades c-di-GMP.
基因功能參考文獻：
1. Results suggest that STM1697 and STM1344 belong to a subclass of EAL domain proteins in S. typhimurium, which are all involved in motility,biofilm and virulence regulation through interaction with proteins that regulate flagella function. PMID: 24127899
2. Salmonella mutants lacking YdiV are unable to fully repress flagellin at systemic sites, rendering them vulnerable to caspase-1 mediated colonization restriction PMID: 22143773
3. The results indicate that FliZ is a repressor of the nlpC-ydiV operon and activates the class 2 operons by repressing ydiV expression. Therefore, the fliZ and ydiV genes form a regulatory loop. PMID: 21804009
4. This study showed that flagellar expression was much reduced in the cells grown in poor medium; it was concluded that YdiV is a novel anti-FlhD(4)C(2) factor responsible for nutritional control of the flagellar regulon. PMID: 21278297
蛋白家族：

YdiV family
數據庫鏈接：

KEGG: stm:STM1344

STRING: 99287.STM1344