Recombinant Salmonella typhimurium Cell invasion protein sipD (sipD)

中文名稱：

鼠傷寒沙門菌sipD重組蛋白
貨號：

CSB-YP710019SXB
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

鼠傷寒沙門菌sipD重組蛋白
貨號：

CSB-EP710019SXB-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

鼠傷寒沙門菌sipD重組蛋白
貨號：

CSB-BP710019SXB
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

鼠傷寒沙門菌sipD重組蛋白
貨號：

CSB-MP710019SXB
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

sipD
Uniprot No.：

Q56026
別名：

sipD; sspD; STM2883; Cell invasion protein SipD; Salmonella invasion protein D
種屬：

Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
蛋白長度：

full length protein
表達區域：

1-343
氨基酸序列

MLNIQNYSAS PHPGIVAERP QTPSASEHVE TAVVPSTTEH RGTDIISLSQ AATKIHQAQQ TLQSTPPISE ENNDERTLAR QQLTSSLNAL AKSGVSLSAE QNENLRSAFS APTSALFSAS PMAQPRTTIS DAEIWDMVSQ NISAIGDSYL GVYENVVAVY TDFYQAFSDI LSKMGGWLLP GKDGNTVKLD VTSLKNDLNS LVNKYNQINS NTVLFPAQSG SGVKVATEAE ARQWLSELNL PNSCLKSYGS GYVVTVDLTP LQKMVQDIDG LGAPGKDSKL EMDNAKYQAW QSGFKAQEEN MKTTLQTLTQ KYSNANSLYD NLVKVLSSTI SSSLETAKSF LQG
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of SipA, SipB, and SipC.
基因功能參考文獻：
1. The N-terminal domain of the Salmonella SipB translocon protein interacts with the SipD tip protein at a surface at the distal region of the tip formed by the mixed alpha/beta domain and a portion of its coiled-coil domain. PMID: 27093649
2. the crystal structures of SipD in complex with the bile salts deoxycholate and chenodeoxycholate PMID: 21031487
3. Protein translocases SipB, SipC, and SipD of the Salmonella enterica serovar Typhimurium pathogenicity island 1 (SPI-1)-encoded TTSS are required for the intimate association of these bacteria with mammalian cells. PMID: 19364837
亞細胞定位：

Secreted. Note=Secreted via the type III secretion system 1 (SPI-1 TTSS).
蛋白家族：

Invasin protein D family
數據庫鏈接：

KEGG: stm:STM2883

STRING: 99287.STM2883