Recombinant Saccharomyces cerevisiae Vacuolar fusion protein CCZ1 (CCZ1), partial

中文名稱：

Recombinant Saccharomyces cerevisiae Vacuolar fusion protein CCZ1(CCZ1) ,partial
貨號：

CSB-YP330851SVG
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae Vacuolar fusion protein CCZ1(CCZ1) ,partial
貨號：

CSB-EP330851SVG
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae Vacuolar fusion protein CCZ1(CCZ1) ,partial
貨號：

CSB-EP330851SVG-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae Vacuolar fusion protein CCZ1(CCZ1) ,partial
貨號：

CSB-BP330851SVG
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae Vacuolar fusion protein CCZ1(CCZ1) ,partial
貨號：

CSB-MP330851SVG
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

CCZ1
Uniprot No.：

P38273
別名：

CCZ1; AUT11; CVT16; YBR131W; YBR1006Vacuolar fusion protein CCZ1; Autophagy-related protein 11; Calcium-caffeine-zinc sensitivity protein 1; Cytoplasm to vacuole targeting protein 16
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

In complex with MON1, is required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis. The CCZ1-MON1 complex acts at the fusion of vesicles with the vacuole, through its regulation of the SNARE complex during the coordinated priming and docking stages of fusion, and particularly at the stage of tethering/docking. The CCZ1-MON1 complex acts as a guanine nucleotide-exchange factor (GEF) for Rab-type GTPase YPT7, promoting nucleotide exchange on YPT7 and triggering endosomal maturation by activating YPT7 on late endosomes.
基因功能參考文獻：
1. Guanine nucleotide exchange factor activity of the Mon1-Ccz1 complex towards Ypt7 requires the interface formed by their longin domains. PMID: 24413168
2. Data indicate that the Mon1-Ccz1 complex triggers endosomal maturation by activating Ypt7 on late endosomes. PMID: 20797862
3. vacuolar sorting protein Ccz1p has multiple functions in Saccharomyces cerevisiae PMID: 15721293
4. These results suggest that the Ccz1p-Mon1p-Ypt7p complex is involved in fusion of transport vesicles to multiple target membranes in yeast cells. PMID: 19456873
亞細胞定位：

Endosome, multivesicular body membrane; Peripheral membrane protein. Prevacuolar compartment membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Note=The association of the CCZ1-MON1 complex with the vacuole is regulated by the C-Vps/HOPS complex.
蛋白家族：

CCZ1 family
數據庫鏈接：

KEGG: sce:YBR131W

STRING: 4932.YBR131W