Recombinant Saccharomyces cerevisiae Protein SCM3 (SCM3)

中文名稱：

釀酒酵母SCM3重組蛋白
貨號：

CSB-YP623609SVG
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

釀酒酵母SCM3重組蛋白
貨號：

CSB-EP623609SVG
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

釀酒酵母SCM3重組蛋白
貨號：

CSB-EP623609SVG-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

釀酒酵母SCM3重組蛋白
貨號：

CSB-BP623609SVG
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

釀酒酵母SCM3重組蛋白
貨號：

CSB-MP623609SVG
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

SCM3
Uniprot No.：

Q12334
別名：

SCM3; YDL139C; D2155; Protein SCM3; Suppressor of chromosome missegregation protein 3
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

full length protein
表達區域：

1-223
氨基酸序列

MKTNKKISKR RSLKNLHGAL KGLLKESGKK SESKIRKHSD CNPVHRVYPP NIEKRKTKKD DGISRPIAER NGHVYIMSKE NHIIPKLTDD EVMERHKLAD ENMRKVWSNI ISKYESIEEQ GDLVDLKTGE IVEDNGHIKT LTANNSTKDK RTKYTSVLRD IIDISDEEDG DKNDEYTLWA NDSEASDSEV DADNDTEEEK DEKLIDADFK KYEAKLSKRI LRD
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

基因功能參考文獻：
1. Cse4 and H3 are structurally compatible to be incorporated in the same nucleosome to form heterotypic particles during Scm3-mediated nucleosome assembly. PMID: 24623811
2. Scm3 becomes 2.5-fold enriched at kinetochores in anaphase after incorporation of Ces4 and then dissociated from kinetochores with mitotic exit. PMID: 21926480
3. stringent regulation of HJURP and SCM3 expression are critical for genome stability. PMID: 21980305
4. Scm3 functions as a Cse4-specific nucleosome assembly factor, and the resulting octameric nucleosomes do not contain Scm3 as a stably bound component. PMID: 21587230
5. Study propose that Scm3 plays an active role in centromeric nucleosome assembly. PMID: 21317428
6. Ndc10/Scm3 binds to centromeric DNA, which is in turn essential for targeting Cse4 to centromeres. PMID: 17569568
7. nonhistone Scm3 serves to assemble and maintain Cse4-H4 at centromeres and may replace histone H2A-H2B dimers in a centromere-specific nucleosome core PMID: 17574026
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亞細胞定位：

Nucleus.
數據庫鏈接：

KEGG: sce:YDL139C

STRING: 4932.YDL139C