Recombinant Ribosomal RNA large subunit methyltransferase Cfr (cfr)

中文名稱：

Recombinant Ribosomal RNA large subunit methyltransferase Cfr(cfr)
貨號：

CSB-YP880701SGAI
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Ribosomal RNA large subunit methyltransferase Cfr(cfr)
貨號：

CSB-EP880701SGAI
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Ribosomal RNA large subunit methyltransferase Cfr(cfr)
貨號：

CSB-EP880701SGAI-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Ribosomal RNA large subunit methyltransferase Cfr(cfr)
貨號：

CSB-BP880701SGAI
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Ribosomal RNA large subunit methyltransferase Cfr(cfr)
貨號：

CSB-MP880701SGAI
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

cfr
Uniprot No.：

Q9FBG4
別名：

cfr; Ribosomal RNA large subunit methyltransferase Cfr; EC 2.1.1.224; 23S rRNA; adenine(2503)-C(8))-methyltransferase; 23S rRNA m8A2503 methyltransferase
種屬：

Staphylococcus sciuri
蛋白長度：

full length protein
表達區域：

1-349
氨基酸序列

MNFNNKTKYG KIQEFLRSNN EPDYRIKQIT NAIFKQRISR FEDMKVLPKL LREDLINNFG ETVLNIKLLA EQNSEQVTKV LFEVSKNERV ETVNMKYKAG WESFCISSQC GCNFGCKFCA TGDIGLKKNL TVDEITDQVL YFHLLGHQID SISFMGMGEA LANRQVFDAL DSFTDPNLFA LSPRRLSIST IGIIPSIKKI TQEYPQVNLT FSLHSPYSEE RSKLMPINDR YPIDEVMNIL DEHIRLTSRK VYIAYIMLPG VNDSLEHANE VVSLLKSRYK SGKLYHVNLI RYNPTISAPE MYGEANEGQV EAFYKVLKSA GIHVTIRSQF GIDIDAACGQ LYGNYQNSQ
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Specifically methylates position 8 of adenine 2503 in 23S rRNA. Can also methylate position 2 of A2503 after the primary methylation at position 8 is complete, to form 2,8-dimethyladenosine; however, C8 is its preferred target. Confers resistance to several classes of antibiotics such as phenicols, lincosamides, oxazolidinones, pleuromutilins, and streptogramin A. The antibiotic resistance conferred by Cfr is provided by methylation at the 8 position and is independent of methylation at the 2 position of A2503.
基因功能參考文獻：
1. A multidrug resistance gene cfr was detected in isolates of clonal lineages, rendering a spread to humans with exposure to swine farming possible PMID: 19047652
亞細胞定位：

Cytoplasm.
蛋白家族：

Radical SAM superfamily, RlmN family, Cfr subfamily
數據庫鏈接：

KEGG: ag:CAE18142