Recombinant Rat Unconventional myosin-Id (Myo1d), partial

中文名稱：

大鼠Myo1d重組蛋白
貨號：

CSB-YP733927RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Myo1d重組蛋白
貨號：

CSB-EP733927RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Myo1d重組蛋白
貨號：

CSB-EP733927RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Myo1d重組蛋白
貨號：

CSB-BP733927RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Myo1d重組蛋白
貨號：

CSB-MP733927RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Myo1d
Uniprot No.：

Q63357
別名：

Myo1d; Myr4; Unconventional myosin-Id; Myosin heavy chain myr 4
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Unconventional myosin that functions as actin-based motor protein with ATPase activity. Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes. Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells.
基因功能參考文獻：
1. This study demonistrated that myosin ID is expressed in myelinating oligodendrocytes in rat nerve system. PMID: 24903835
2. In conclusion, for the surface loops of Myo1c explored to date, the parent myosin dominates the behavior and loop 1 modulates the properties of the parent myosin. The loops themselves do not confer predictable properties on the parent myosin. PMID: 20039646
3. At apical surfaces of supporting cells surrounding hair cells in auditory epithelia of postnatal rats. In vestibular epithelia, in a ring within apical pole of hair cell. Prominent only immediately after birth. PMID: 12486594
4. Results support a model in which Myo1c possesses a strain-sensing ADP-release mechanism, which allows it to adapt to mechanical load. PMID: 15014434
5. Myr4 mRNA was abundant in spinal cord motor neurons PMID: 15809075
6. Results describe Myo1d ATPase activity as a function of its IQ-motifs and calcium-calmodulin binding. PMID: 15853803
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亞細胞定位：

Cytoplasm. Perikaryon. Cell projection, dendrite. Early endosome. Cytoplasm, cell cortex.
蛋白家族：

TRAFAC class myosin-kinesin ATPase superfamily, Myosin family
組織特異性：

Detected on tracheal epithelial cells, and on epithelial cells and brush border cells in duodenum, jejunum and ileum. Detected on myelinated white matter in the cerebellum, and the myelinated part of the optic nerve. Detected on mature oligodendrocites. D
數據庫鏈接：

KEGG: rno:25485

STRING: 10116.ENSRNOP00000004609

UniGene: Rn.10376