Recombinant Rat UPF0667 protein C1orf55 homolog

中文名稱：

大鼠Sde2重組蛋白
貨號：

CSB-YP685588RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

大鼠Sde2重組蛋白
貨號：

CSB-EP685588RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

大鼠Sde2重組蛋白
貨號：

CSB-EP685588RA-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Sde2重組蛋白
貨號：

CSB-BP685588RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Sde2重組蛋白
貨號：

CSB-MP685588RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Sde2
Uniprot No.：

Q5BJN8
別名：

Sde2; Replication stress response regulator SDE2
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達(dá)區(qū)域：

1-448
氨基酸序列

MAEAAVLAWV RGPGTAWKAL PCASVGCSVR DVIYRHCEEQ EIPVECFFVK CNGVLVAAGD KVCHGAVYSL EPRLRGGKGG FGSMLRALGA QIEKTTNREA CRDLSGRRLR DVNHEKAMAE WVKQQAEREA EKEQRRLERL QRKLAEPAHC FASPDYQRQC HEMAERLEDS VLKGMQAASS KVVSAEVTET RKRPNRSKTD QGAGAKKKRC FWLGMEGLEA AEGSSTGSSD DSEDDDHEDA PGTSGPSCCA RENGSDGGEV AADSPGSVQS SGSGTRSESP KELQNPMTEP GQGILENTGT EPGETSTREH NERKTVTVTE TEETPARKET ESPEPTEKGQ ETGVIGEDRA AMALSGEDRK SIPAATPEGS NSGDTALGVE ALDLSAFSCA AELELLGLER LKCALMALGL KCGGTLQERA ARLFSVRGLS KELIDPTLFA KPSKGKKK
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

功能：

Involved in both DNA replication and cell cycle control. Unprocessed SDE2 interacts with PCNA via its PIP-box. The interaction with PCNA prevents monoubiquitination of the latter thereby inhibiting translesion DNA synthesis. The binding of SDE2 to PCNA also leads to processing of SDE2 by an unidentified deubiquitinating enzyme, cleaving off the N-terminal ubiquitin-like domain. The resulting mature SDE2 is degraded by the DCX(DTL) complex in a cell cycle- and DNA damage dependent manner. Binding of SDE2 to PCNA is necessary to counteract damage due to ultraviolet light induced replication stress. The complete degradation of SDE2 is necessary to allow S-phase progression.
亞細(xì)胞定位：

Nucleus.
蛋白家族：

SDE2 family
數(shù)據(jù)庫鏈接：

KEGG: rno:289315

STRING: 10116.ENSRNOP00000004350

UniGene: Rn.16374