Recombinant Rat Transmembrane protein 132A (Tmem132a), partial

中文名稱：

大鼠Tmem132a重組蛋白
貨號：

CSB-YP023699RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Tmem132a重組蛋白
貨號：

CSB-EP023699RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Tmem132a重組蛋白
貨號：

CSB-EP023699RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Tmem132a重組蛋白
貨號：

CSB-BP023699RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Tmem132a重組蛋白
貨號：

CSB-MP023699RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Tmem132a
Uniprot No.：

Q80WF4
別名：

Tmem132a; Gbp; Hspa5bp1; Transmembrane protein 132A; GRP78-binding protein; HSPA5-binding protein 1
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May play a role in embryonic and postnatal development of the brain. Increased resistance to cell death induced by serum starvation in cultured cells. Regulates cAMP-induced GFAP gene expression via STAT3 phosphorylation.
基因功能參考文獻：
1. GRP78 in astroglia could strongly chelate with Pb ions. PMID: 19662369
2. Mitochondrial calcium-mediated reactive oxygen species are essential for the rapid transactivation of the grp78 gene. PMID: 12401520
3. cloning and characterization of GRP78-binding protein that plays a role in embryonic and postnatal development of the brain PMID: 12514190
4. These results suggest a novel function of GBP in regulating GFAP gene expression via STAT3 phosphorylation. PMID: 16806201
5. GRP78 is involved in IL-6 secretion from astrocytes, and lead can block IL-6 secretion from astrocytes via targeting GRP78 PMID: 17567751
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亞細胞定位：

Golgi apparatus membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
蛋白家族：

TMEM132 family
組織特異性：

Expressed in the brain in neuronal cells of the hypothalamus, thalamus, cerebral cortex, amygdala, and cerebellum.
數據庫鏈接：

KEGG: rno:338474

STRING: 10116.ENSRNOP00000037012

UniGene: Rn.160719