Recombinant Rat Testosterone 17-beta-dehydrogenase 3 (Hsd17b3)

中文名稱：

大鼠Hsd17b3重組蛋白
貨號：

CSB-YP010773RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

大鼠Hsd17b3重組蛋白
貨號：

CSB-EP010773RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

大鼠Hsd17b3重組蛋白
貨號：

CSB-EP010773RA-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Hsd17b3重組蛋白
貨號：

CSB-BP010773RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Hsd17b3重組蛋白
貨號：

CSB-MP010773RA
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Hsd17b3
Uniprot No.：

O54939
別名：

Hsd17b3; Edh17b3; Testosterone 17-beta-dehydrogenase 3; EC 1.1.1.64; 17-beta-hydroxysteroid dehydrogenase type 3; 17-beta-HSD 3; Testicular 17-beta-hydroxysteroid dehydrogenase
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full length protein
表達區(qū)域：

1-306
氨基酸序列

MEQFLLSVGL LVCLVCLVKC VRFSRYLFLS FCKALPGSFL RSMGQWAVIT GAGDGIGKAY SFELARHGLN VVLISRTLEK LQVISEEIER TTGSRVKVVQ ADFTREDIYD HIEEQLKGLE IGVLVNNVGM LPNLLPSHFL STSGESQSVI HCNITSVVKM TQLVLKHMES RRRGLILNIS SGVGVRPWPL YSLYSASKAF VCTFSKALNV EYRDKGIIIQ VLTPYSVSTP MTKYLNTSRV TKTADEFVKE SLKYVTIGAE TCGCLAHEIL AIILNLIPSR IFYSSTTQRF LLKQFSDYLK SNISNR
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 668
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Favors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH. Androgens such as epiandrosterone, dehydroepiandrosterone, androsterone and androstanedione are accepted as substrates and reduced at C-17. Can reduce 11-ketoandrostenedione as well as 11beta-hydroxyandrostenedione at C-17 to the respective testosterone forms.
基因功能參考文獻：
1. compared (+)- and (-)-gossypols in the inhibition of 3beta-HSD and 17beta-HSD3 in human and rat testes PMID: 19429456
亞細胞定位：

Endoplasmic reticulum.
蛋白家族：

Short-chain dehydrogenases/reductases (SDR) family, 17-beta-HSD 3 subfamily
數(shù)據(jù)庫鏈接：

KEGG: rno:117182

STRING: 10116.ENSRNOP00000025850

UniGene: Rn.10895